U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

OR52L1 olfactory receptor family 52 subfamily L member 1 [ Homo sapiens (human) ]

Gene ID: 338751, updated on 27-Nov-2024

Summary

Official Symbol
OR52L1provided by HGNC
Official Full Name
olfactory receptor family 52 subfamily L member 1provided by HGNC
Primary source
HGNC:HGNC:14785
See related
Ensembl:ENSG00000183313 AllianceGenome:HGNC:14785
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR11-50
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See OR52L1 in Genome Data Viewer
Location:
11p15.4
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (5985892..5986985, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (6044395..6045488, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (6007122..6008215, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 56 subfamily A member 3 Neighboring gene olfactory receptor family 56 subfamily A member 5 Neighboring gene uncharacterized LOC124902621 Neighboring gene keratin 18 pseudogene 58 Neighboring gene olfactory receptor family 56 subfamily A member 4

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
olfactory receptor 52L1
Names
olfactory receptor OR11-50

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005173.3NP_001005173.3  olfactory receptor 52L1

    See identical proteins and their annotated locations for NP_001005173.3

    Status: VALIDATED

    Source sequence(s)
    AC111177, KF570259
    Consensus CDS
    CCDS44529.1
    UniProtKB/Swiss-Prot
    B2RPA6, Q6IFK9, Q8NGH7
    UniProtKB/TrEMBL
    A0A126GVE0
    Related
    ENSP00000330338.4, ENST00000332249.4
    Conserved Domains (1) summary
    cl21561
    Location:52328
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    5985892..5986985 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    6044395..6045488 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)