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VSIG10L2 V-set and immunoglobulin domain containing 10 like 2 [ Homo sapiens (human) ]

Gene ID: 338667, updated on 4-Nov-2022

Summary

Official Symbol
VSIG10L2provided by HGNC
Official Full Name
V-set and immunoglobulin domain containing 10 like 2provided by HGNC
Primary source
HGNC:HGNC:27879
See related
Ensembl:ENSG00000283703 AllianceGenome:HGNC:27879
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable cell adhesion molecule binding activity. Predicted to be involved in cell-cell adhesion. Predicted to be active in cell-cell junction. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in skin (RPKM 3.2), spleen (RPKM 0.6) and 1 other tissue See more
Orthologs
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Genomic context

See VSIG10L2 in Genome Data Viewer
Location:
11q24.2
Exon count:
12
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (125946044..125956319)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (125974898..125985173)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (125815939..125826214)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene HYLS1 centriolar and ciliogenesis associated Neighboring gene pseudouridine synthase 3 Neighboring gene DEAD-box helicase 25 Neighboring gene cell adhesion associated, oncogene regulated Neighboring gene VISTA enhancer hs1641 Neighboring gene nucleosome assembly protein 1 like 1 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables cell adhesion molecule binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cell-cell junction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
V-set and immunoglobulin domain-containing protein 10-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001365077.2NP_001352006.1  V-set and immunoglobulin domain-containing protein 10-like 2 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AP000842
    Consensus CDS
    CCDS91619.1
    UniProtKB/TrEMBL
    A0A8I5KPR9
    Related
    ENSP00000509422.1, ENST00000686984.1
    Conserved Domains (3) summary
    smart00410
    Location:508594
    IG_like; Immunoglobulin like
    pfam00041
    Location:598689
    fn3; Fibronectin type III domain
    pfam13927
    Location:241312
    Ig_3; Immunoglobulin domain
  2. NM_001391971.1NP_001378900.1  V-set and immunoglobulin domain-containing protein 10-like 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AP000842
    Related
    ENSP00000491366.1, ENST00000640497.1
  3. NM_001391972.1NP_001378901.1  V-set and immunoglobulin domain-containing protein 10-like 2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AP000842
    Related
    ENST00000638511.1

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    125946044..125956319
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    125974898..125985173
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)