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H2BP2 H2B histone pseudogene 2 [ Homo sapiens (human) ]

Gene ID: 338391, updated on 10-Oct-2023


Official Symbol
H2BP2provided by HGNC
Official Full Name
H2B histone pseudogene 2provided by HGNC
Primary source
See related
Gene type
RefSeq status
Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is a histone pseudogene found on chromosome 1. [provided by RefSeq, Oct 2015]
Annotation information
Note: HIST2H2BB (GeneID: 338391) was incorrectly annotated at chr1: NC_000001.10:120905664..120906800(+) on NCBI's Build 37.3. Its correct location is chr1: NC_000001.11: 143846902.. 143904650(-). [06 Mar 2019]
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Genomic context

Exon count:
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (143846902..143904650, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (142918942..142976669, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (149341469..149399226, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene PDE4DIP pseudogene 3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:149332654-149333586 Neighboring gene ubiquitin conjugating enzyme E2 D4 (putative) pseudogene Neighboring gene tRNA-Arg (anticodon CCT) 7-1 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr1:149362195-149362753 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1255 Neighboring gene Fc gamma receptor Ic, pseudogene Neighboring gene NANOG hESC enhancer GRCh37_chr1:149396107-149396742 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:149398885-149399385 Neighboring gene uncharacterized LOC105371209 Neighboring gene H3.7 histone (putative) Neighboring gene ribosomal protein L22 pseudogene 5 Neighboring gene family with sequence similarity 72 member C Neighboring gene SLIT-ROBO Rho GTPase activating protein 2D (pseudogene)

Genomic regions, transcripts, and products

General gene information

Other Names

  • histone 2, H2bb
  • histone cluster 2 H2B family member b (pseudogene)
  • histone cluster 2, H2bb (pseudogene)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.


  1. NR_160913.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
  2. NR_160914.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
  3. NR_160915.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly


  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    143846902..143904650 complement
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0


  1. NC_060925.1 Alternate T2T-CHM13v2.0

    142918942..142976669 complement
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_002652.3: Suppressed sequence

    NG_002652.3: This RefSeq was removed because it is now thought that this gene is a transcribed pseudogene.