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Ifnl3 interferon lambda 3 [ Mus musculus (house mouse) ]

Gene ID: 338374, updated on 23-May-2018

Summary

Official Symbol
Ifnl3provided by MGI
Official Full Name
interferon lambda 3provided by MGI
Primary source
MGI:MGI:2450574
See related
Ensembl:ENSMUSG00000060747 Vega:OTTMUSG00000059060
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Il28; IFL-1; Il28b; IL-28B; INF-alpha; INF-lambda
Expression
Biased expression in adrenal adult (RPKM 1.2), thymus adult (RPKM 0.2) and 2 other tissues See more

Genomic context

See Ifnl3 in Genome Data Viewer
Location:
7; 7 B1
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (28522833..28524401)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (29307855..29309341)

Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8 pseudogene Neighboring gene interferon lambda 2 Neighboring gene cytochrome c, somatic pseudogene Neighboring gene syncollin

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
cytokine activity IEA
Inferred from Electronic Annotation
more info
 
signaling receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
signaling receptor binding ISA
Inferred from Sequence Alignment
more info
PubMed 
Process Evidence Code Pubs
JAK-STAT cascade IEA
Inferred from Electronic Annotation
more info
 
defense response to virus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
innate immune response IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of immune response IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
extracellular space IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
interferon lambda-3
Names
IFN-lambda-3
interferon alpha
interleukin 28
interleukin-28B

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177396.1NP_796370.1  interferon lambda-3 precursor

    See identical proteins and their annotated locations for NP_796370.1

    Status: PROVISIONAL

    Source sequence(s)
    AY184375
    Consensus CDS
    CCDS21047.1
    UniProtKB/Swiss-Prot
    Q8CGK6
    Related
    ENSMUSP00000077473.3, OTTMUSP00000075488, ENSMUST00000078364.3, OTTMUST00000144890
    Conserved Domains (1) summary
    pfam15177
    Location:32189
    IL28A; Interleukin-28A

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

    Range
    28522833..28524401
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006540130.1XP_006540193.1  interferon lambda-3 isoform X1

    Conserved Domains (1) summary
    pfam15177
    Location:32142
    IL28A; Interleukin-28A
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