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CHRNA1 cholinergic receptor nicotinic alpha 1 subunit [ Bos taurus (cattle) ]

Gene ID: 338070, updated on 8-Jul-2021

Summary

Official Symbol
CHRNA1provided by VGNC
Official Full Name
cholinergic receptor nicotinic alpha 1 subunitprovided by VGNC
Primary source
VGNC:VGNC:27322
See related
BGD:BT11902; Ensembl:ENSBTAG00000018253
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
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Genomic context

See CHRNA1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
9
Annotation release Status Assembly Chr Location
106 current ARS-UCD1.2 (GCF_002263795.1) 2 NC_037329.1 (22084351..22103937)
105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 2 AC_000159.1 (22120291..22139878)

Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene activating transcription factor 2 Neighboring gene chimerin 1 Neighboring gene uncharacterized LOC107132239 Neighboring gene WAS/WASL interacting protein family member 1 Neighboring gene non-histone chromosomal protein HMG-14 pseudogene

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables acetylcholine binding IEA
Inferred from Electronic Annotation
more info
 
enables acetylcholine receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables acetylcholine-gated cation-selective channel activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in excitatory postsynaptic potential IEA
Inferred from Electronic Annotation
more info
 
involved_in muscle cell cellular homeostasis IEA
Inferred from Electronic Annotation
more info
 
involved_in neuromuscular junction development IEA
Inferred from Electronic Annotation
more info
 
involved_in neuromuscular synaptic transmission IEA
Inferred from Electronic Annotation
more info
 
involved_in neuron cellular homeostasis IEA
Inferred from Electronic Annotation
more info
 
involved_in neuronal action potential IEA
Inferred from Electronic Annotation
more info
 
involved_in skeletal muscle contraction IEA
Inferred from Electronic Annotation
more info
 
involved_in skeletal muscle tissue growth IEA
Inferred from Electronic Annotation
more info
 
involved_in synaptic transmission, cholinergic IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of acetylcholine-gated channel complex IEA
Inferred from Electronic Annotation
more info
 
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of postsynaptic specialization membrane IEA
Inferred from Electronic Annotation
more info
 
located_in neuromuscular junction IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
acetylcholine receptor subunit alpha
Names
cholinergic receptor, nicotinic, alpha 1 (muscle)
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_176664.2NP_788837.1  acetylcholine receptor subunit alpha precursor

    See identical proteins and their annotated locations for NP_788837.1

    Status: PROVISIONAL

    Source sequence(s)
    X02509
    UniProtKB/Swiss-Prot
    P02709
    Related
    ENSBTAP00000024298.5, ENSBTAT00000024298.6
    Conserved Domains (2) summary
    pfam02931
    Location:24231
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:238446
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD1.2 Primary Assembly

Genomic

  1. NC_037329.1 Reference ARS-UCD1.2 Primary Assembly

    Range
    22084351..22103937
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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