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Myod1 myogenic differentiation 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 337868, updated on 2-Oct-2021

Summary

Official Symbol
Myod1provided by RGD
Official Full Name
myogenic differentiation 1provided by RGD
Primary source
RGD:631429
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
transcription factor; involved in muscle cell differentiation [RGD, Feb 2006]
Expression
Restricted expression toward (RPKM 57.3) See more
Orthologs
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Genomic context

See Myod1 in Genome Data Viewer
Location:
1q22
Exon count:
3
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (96884864..96887574)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (102396538..102399248)

Chromosome 1 - NC_051336.1Genomic Context describing neighboring genes Neighboring gene USH1 protein network component harmonin Neighboring gene otogelin Neighboring gene uncharacterized LOC120099806 Neighboring gene potassium voltage-gated channel subfamily C member 1 Neighboring gene secretion regulating guanine nucleotide exchange factor Neighboring gene uncharacterized LOC120099807

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Markers

Homology

Clone Names

  • MGC156574

Gene Ontology Provided by RGD

Function Evidence Code Pubs
contributes_to DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables DNA-binding transcription activator activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription activator activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
 
enables DNA-binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables E-box binding IDA
Inferred from Direct Assay
more info
PubMed 
enables E-box binding IEA
Inferred from Electronic Annotation
more info
 
enables E-box binding ISO
Inferred from Sequence Orthology
more info
 
enables E-box binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables RNA polymerase II-specific DNA-binding transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
enables chromatin DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables chromatin DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables chromatin DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables chromatin binding ISO
Inferred from Sequence Orthology
more info
 
enables chromatin binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables cis-regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables enzyme binding ISO
Inferred from Sequence Orthology
more info
 
enables nuclear receptor binding IEA
Inferred from Electronic Annotation
more info
 
enables nuclear receptor binding ISO
Inferred from Sequence Orthology
more info
 
enables promoter-specific chromatin binding IEA
Inferred from Electronic Annotation
more info
 
enables promoter-specific chromatin binding ISO
Inferred from Sequence Orthology
more info
 
enables promoter-specific chromatin binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
enables sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables sequence-specific double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables ubiquitin protein ligase binding IEA
Inferred from Electronic Annotation
more info
 
enables ubiquitin protein ligase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in cellular response to estradiol stimulus IEA
Inferred from Electronic Annotation
more info
 
involved_in cellular response to estradiol stimulus ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to estradiol stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cellular response to glucocorticoid stimulus IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cellular response to glucocorticoid stimulus ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to oxygen levels IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cellular response to oxygen levels ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to starvation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cellular response to starvation ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to tumor necrosis factor IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cellular response to tumor necrosis factor ISO
Inferred from Sequence Orthology
more info
 
involved_in histone H3 acetylation IEA
Inferred from Electronic Annotation
more info
 
involved_in histone H3 acetylation ISO
Inferred from Sequence Orthology
more info
 
involved_in histone H3 acetylation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in histone H4 acetylation IEA
Inferred from Electronic Annotation
more info
 
involved_in histone H4 acetylation ISO
Inferred from Sequence Orthology
more info
 
involved_in histone H4 acetylation ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within muscle organ development ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within myoblast differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in myoblast differentiation ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in myoblast fate determination IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within myoblast fate determination ISO
Inferred from Sequence Orthology
more info
 
involved_in myoblast fate determination ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in myoblast fusion IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within myoblast fusion ISO
Inferred from Sequence Orthology
more info
 
involved_in myotube cell development ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within myotube differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in myotube differentiation involved in skeletal muscle regeneration IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within myotube differentiation involved in skeletal muscle regeneration ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of chromatin binding IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of chromatin binding ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of myoblast proliferation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within negative regulation of myoblast proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of binding IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of binding ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of muscle cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of muscle cell differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of muscle cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of myoblast differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of myoblast fusion IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of myoblast fusion ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of skeletal muscle fiber development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of skeletal muscle tissue regeneration IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within positive regulation of skeletal muscle tissue regeneration ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of skeletal muscle tissue regeneration ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in positive regulation of snRNA transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of snRNA transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of snRNA transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
acts_upstream_of_or_within positive regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of RNA splicing ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of alternative mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within regulation of alternative mRNA splicing, via spliceosome ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of alternative mRNA splicing, via spliceosome ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in response to muscle stretch IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in skeletal muscle atrophy IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in skeletal muscle cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in skeletal muscle cell differentiation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within skeletal muscle cell differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in skeletal muscle cell differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in skeletal muscle fiber adaptation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within skeletal muscle fiber adaptation ISO
Inferred from Sequence Orthology
more info
 
involved_in skeletal muscle fiber development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within skeletal muscle fiber development ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within skeletal muscle tissue development ISO
Inferred from Sequence Orthology
more info
 
involved_in skeletal muscle tissue development ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in skeletal muscle tissue regeneration IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in skeletal muscle tissue regeneration IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in skeletal muscle tissue regeneration ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within striated muscle cell differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in striated muscle cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Component Evidence Code Pubs
located_in chromatin ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in euchromatin IEA
Inferred from Electronic Annotation
more info
 
located_in euchromatin ISO
Inferred from Sequence Orthology
more info
 
located_in myofibril IEA
Inferred from Electronic Annotation
more info
 
located_in myofibril ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 
part_of transcription regulator complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
myoblast determination protein 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_176079.2NP_788268.2  myoblast determination protein 1

    Status: PROVISIONAL

    Source sequence(s)
    JACYVU010000033
    Conserved Domains (3) summary
    smart00520
    Location:19114
    BASIC; Basic domain in HLH proteins of MYOD family
    cd18936
    Location:105165
    bHLH_TS_MYOD1_Myf3; basic helix-loop-helix (bHLH) domain found in myoblast determination protein 1 (MYOD1) and similar proteins
    pfam12232
    Location:190258
    Myf5; Myogenic determination factor 5

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051336.1 Reference mRatBN7.2 Primary Assembly

    Range
    96884864..96887574
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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