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lamb2 laminin, beta 2 (laminin S) [ Danio rerio (zebrafish) ]

Gene ID: 337767, updated on 6-May-2021

Summary

Official Symbol
lamb2provided by ZNC
Official Full Name
laminin, beta 2 (laminin S)provided by ZNC
Primary source
ZFIN:ZDB-GENE-081030-4
See related
Ensembl:ENSDARG00000002084
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
s; si:dkey-32e6.2
Orthologs
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Genomic context

See lamb2 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
35
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (20179532..20259526, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (20253204..20333194, complement)
103 previous assembly Zv9 (GCF_000002035.4) 23 NC_007134.5 (20468084..20548062, complement)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene si:dkey-32e6.3 Neighboring gene ubiquitin specific peptidase 19 Neighboring gene laminin, beta 2-like Neighboring gene si:rp71-17i16.6

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables extracellular matrix structural constituent IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables integrin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in animal organ morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in basement membrane assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within basement membrane assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cell migration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within glial cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within muscle attachment IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within retina development in camera-type eye IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within somite development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in substrate adhesion-dependent cell spreading IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in tissue development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of laminin complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
laminin subunit beta-2
Names
sof
softy

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001243045.1NP_001229974.1  laminin subunit beta-2 precursor

    Status: PROVISIONAL

    Source sequence(s)
    AL953864
    UniProtKB/TrEMBL
    B7ZDA6
    Related
    ENSDARP00000123269.1, ENSDART00000147326.2
    Conserved Domains (9) summary
    smart00180
    Location:767812
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:860905
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:815863
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:41265
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam04012
    Location:15911774
    PspA_IM30; PspA/IM30 family
    pfam12795
    Location:14591682
    MscS_porin; Mechanosensitive ion channel porin domain
    pfam16043
    Location:14601608
    DUF4795; Domain of unknown function (DUF4795)
    cl09176
    Location:12161324
    FlgN; FlgN protein
    cl21509
    Location:15591736
    ApoLp-III_like; Apolipophorin-III and similar insect proteins

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    20179532..20259526 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005162045.3XP_005162102.1  laminin subunit beta-2 isoform X1

    See identical proteins and their annotated locations for XP_005162102.1

    Conserved Domains (9) summary
    smart00180
    Location:767812
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:860905
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:815863
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:41265
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam04012
    Location:16031786
    PspA_IM30; PspA/IM30 family
    pfam12795
    Location:14711694
    MscS_porin; Mechanosensitive ion channel porin domain
    pfam16043
    Location:14721620
    DUF4795; Domain of unknown function (DUF4795)
    cl09176
    Location:12281336
    FlgN; FlgN protein
    cl21509
    Location:15711748
    ApoLp-III_like; Apolipophorin-III and similar insect proteins
  2. XM_005162046.3XP_005162103.1  laminin subunit beta-2 isoform X1

    See identical proteins and their annotated locations for XP_005162103.1

    Conserved Domains (9) summary
    smart00180
    Location:767812
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:860905
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:815863
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:41265
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam04012
    Location:16031786
    PspA_IM30; PspA/IM30 family
    pfam12795
    Location:14711694
    MscS_porin; Mechanosensitive ion channel porin domain
    pfam16043
    Location:14721620
    DUF4795; Domain of unknown function (DUF4795)
    cl09176
    Location:12281336
    FlgN; FlgN protein
    cl21509
    Location:15711748
    ApoLp-III_like; Apolipophorin-III and similar insect proteins
  3. XM_017353525.2XP_017209014.1  laminin subunit beta-2 isoform X1

    Conserved Domains (9) summary
    smart00180
    Location:767812
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:860905
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:815863
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:41265
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam04012
    Location:16031786
    PspA_IM30; PspA/IM30 family
    pfam12795
    Location:14711694
    MscS_porin; Mechanosensitive ion channel porin domain
    pfam16043
    Location:14721620
    DUF4795; Domain of unknown function (DUF4795)
    cl09176
    Location:12281336
    FlgN; FlgN protein
    cl21509
    Location:15711748
    ApoLp-III_like; Apolipophorin-III and similar insect proteins
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