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gnpat2 glyceronephosphate O-acyltransferase 2 [ Danio rerio (zebrafish) ]

Gene ID: 336430, updated on 4-Jan-2025

Summary

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Official Symbol
gnpat2provided by ZNC
Official Full Name
glyceronephosphate O-acyltransferase 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-8374
See related
Ensembl:ENSDARG00000078770 AllianceGenome:ZFIN:ZDB-GENE-030131-8374
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fb10c10; wu:fb10c10; si:ch73-21k16.5
Summary
Predicted to enable O-acyltransferase activity. Predicted to act upstream of or within lipid metabolic process. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in rhizomelic chondrodysplasia punctata type 2. Orthologous to human GNPAT (glyceronephosphate O-acyltransferase). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See gnpat2 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (46924413..46946636)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (47020660..47042796)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene G patch domain containing 2 Neighboring gene lipin 1b Neighboring gene DNA (cytosine-5-)-methyltransferase 3 alpha a Neighboring gene U1 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Developmental roles of D-bifunctional protein-A zebrafish model of peroxisome dysfunction. Kim YI, et al. Mol Cells, 2014 Jan. PMID 24552713, Free PMC Article
  2. Insights Into the Peroxisomal Protein Inventory of Zebrafish. Kamoshita M, et al. Front Physiol, 2022. PMID 35295584, Free PMC Article
  3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables O-acyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
dihydroxyacetone phosphate acyltransferase; uncharacterized protein LOC336430

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    46924413..46946636
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002665777.7 → XP_002665823.3  dihydroxyacetone phosphate acyltransferase

    UniProtKB/TrEMBL
    A0A8M1RMJ8
    Related
    ENSDARP00000118109.2, ENSDART00000132161.4
    Conserved Domains (1) summary
    cd07993
    Location:111 → 316
    LPLAT_DHAPAT-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like
Nucleotide Protein
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