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atg2 autophagy-associated protein Atg2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 3361214, updated on 30-Jul-2025
Official Symbol
atg2
Official Full Name
autophagy-associated protein Atg2
Primary source
PomBase:SPBC31E1.01c
Locus tag
SPOM_SPBC31E1.01C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
mug36; SPBC660.18c
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Location:
chromosome: II
Exon count:
2
Sequence:
Chromosome: II; NC_003423.3 (234477..239599, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene phosphogluconate dehydrogenase Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene P-type calcium transport ATPase Pmr1 Neighboring gene ncRNA Neighboring gene ubiquitin-like protein modifier Hub1

Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Atg2 mediates direct lipid transfer between membranes for autophagosome formation. Osawa T, et al. Nat Struct Mol Biol, 2019 Apr. PMID 30911189
  2. Inter-organelle lipid transfer: a channel model for Vps13 and chorein-N motif proteins. Lees JA, et al. Curr Opin Cell Biol, 2020 Aug. PMID 32213462, Free PMC Article
  3. A conserved membrane curvature-generating protein is crucial for autophagosome formation in fission yeast. Wang N, et al. Nat Commun, 2023 Aug 8. PMID 37553386, Free PMC Article
  4. Fission yeast Vps1 and Atg8 contribute to oxidative stress resistance. Mikawa T, et al. Genes Cells, 2010 Mar. PMID 20070859
  5. Atg38-Atg8 interaction in fission yeast establishes a positive feedback loop to promote autophagy. Yu ZQ, et al. Autophagy, 2020 Nov. PMID 31941401, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables lipid transfer activity TAS
Traceable Author Statement
more info
 PubMed 
enables phosphatidylinositol-3-phosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein-membrane adaptor activity EXP
Inferred from Experiment
more info
 PubMed 
enables protein-membrane adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in autophagosome assembly EXP
Inferred from Experiment
more info
 PubMed 
involved_in autophagosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in autophagy of mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in glycophagy IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intermembrane phospholipid transfer TAS
Traceable Author Statement
more info
 PubMed 
involved_in macroautophagy IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mitophagy IC
Inferred by Curator
more info
  
involved_in pexophagy IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in piecemeal microautophagy of the nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in reticulophagy IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in phagophore IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in phagophore IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in phagophore assembly site IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in phagophore assembly site IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in phagophore assembly site membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
autophagy-associated protein Atg2

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    234477..239599 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001356244.2 → NP_001342784.1  autophagy-associated protein Atg2 [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O94434, O94649
    Conserved Domains (3) summary
    pfam09333
    Location:1554 → 1643
    ATG_C; Autophagy-related protein C terminal domain
    pfam12624
    Location:26 → 134
    Chorein_N; N-terminal region of Chorein or VPS13
    pfam13329
    Location:857 → 1005
    ATG2_CAD; Autophagy-related protein 2 CAD motif
Nucleotide Protein
Heading Accession and Version

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Molecular Biology Databases
Research Materials