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Prx6005 Peroxiredoxin 6005 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33493, updated on 8-Oct-2018

Summary

Official Symbol
Prx6005provided by FlyBase
Official Full Name
Peroxiredoxin 6005provided by FlyBase
Primary source
FLYBASE:FBgn0031479
Locus tag
Dmel_CG3083
Gene type
protein coding
RNA name
peroxiredoxin 6005
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
153181_at; CG3083; Dmel\CG3083; DPx-6005; DPx6005; GM04269p

Genomic context

See Prx6005 in Genome Data Viewer
Location:
23C1-23C1; 2-8 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2877091..2878232, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2877091..2878232, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene beta subunit of type II geranylgeranyl transferase Neighboring gene uncharacterized protein Neighboring gene NTPase

Genomic regions, transcripts, and products

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the Prx6005 gene: The Prx6005 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, M.oryzae, N.crassa, A.thaliana, rice, and frog.

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
peroxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
peroxidase activity IDA
Inferred from Direct Assay
more info
PubMed 
peroxiredoxin activity IEA
Inferred from Electronic Annotation
more info
 
protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
cell redox homeostasis IEA
Inferred from Electronic Annotation
more info
 
cellular response to oxidative stress IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
hydrogen peroxide catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
hydrogen peroxide catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
response to oxidative stress IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
peroxiredoxin 6005
Names
CG3083-PA
Prx6005-PA
NP_523463.2

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    2877091..2878232 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078739.3NP_523463.2  peroxiredoxin 6005 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523463.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VQI7
    Related
    FBpp0077368, FBtr0077684
    Conserved Domains (2) summary
    COG0450
    Location:8198
    AhpC; Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin) [Defense mechanisms]
    cd03016
    Location:8220
    PRX_1cys; Peroxiredoxin (PRX) family, 1-cys PRX subfamily; composed of PRXs containing only one conserved cysteine, which serves as the peroxidatic cysteine. They are homodimeric thiol-specific antioxidant (TSA) proteins that confer a protective role in cells by ...
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