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CG18558 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33482, updated on 4-Apr-2024

Summary

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Official Symbol
CG18558provided by FlyBase
Primary source
FLYBASE:FBgn0031469
Locus tag
Dmel_CG18558
See related
AllianceGenome:FB:FBgn0031469
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
dC1GalT3; Dmel\CG18558
Summary
Predicted to enable glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity. Predicted to be involved in O-glycan processing, core 1. Predicted to be located in membrane. Is expressed in nurse cell and testis. Human ortholog(s) of this gene implicated in Tn polyagglutination syndrome. Orthologous to human C1GALT1C1 (C1GALT1 specific chaperone 1) and C1GALT1C1L (C1GALT1 specific chaperone 1 like). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
23B4-23B4; 2-7 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2842589..2844513, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2842589..2844513, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Cuticular protein 23B Neighboring gene antisense RNA:CR45342 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Requirement for a core 1 galactosyltransferase in the Drosophila nervous system. Lin YR, et al. Dev Dyn, 2008 Dec. PMID 18985719, Free PMC Article
  2. Phenotype-based clustering of glycosylation-related genes by RNAi-mediated gene silencing. Yamamoto-Hino M, et al. Genes Cells, 2015 Jun. PMID 25940448, Free PMC Article
  3. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article
  4. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article
  5. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in O-glycan processing, core 1 IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG18558-PB
NP_608720.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    2842589..2844513 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_134876.3 → NP_608720.2  uncharacterized protein Dmel_CG18558 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608720.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VQH7
    Conserved Domains (1) summary
    cl21608
    Location:400 → 458
    Galactosyl_T; Galactosyltransferase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8T3Z1 Q8T3Z1
Q9VQH7 Q9VQH7

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