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ileS isoleucyl-tRNA synthetase [ Corynebacterium glutamicum ATCC 13032 ]

Gene ID: 3345452, discontinued on 9-Feb-2015
  • All Gene records for this genome have been discontinued due to a change in scope for prokaryotic genomes in Gene. At the time this Gene record was discontinued, the RefSeq genome was re-annotated with the following features at this location:

Summary

Gene symbol
ileS
Gene description
isoleucyl-tRNA synthetase
Locus tag
cg2359
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Corynebacterium glutamicum ATCC 13032 (strain: DSM 20300; ATCC 13032)
Lineage
Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Corynebacterineae; Corynebacteriaceae; Corynebacterium
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General protein information

Names
isoleucyl-tRNA synthetase
YP_226389.1
  • IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_006958.1 Reference assembly

    Range
    2242657..2245821 complement
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_226389.1 isoleucyl-tRNA synthetase [Corynebacterium glutamicum ATCC 13032]

    Status: REVIEWED

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