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Or23a Odorant receptor 23a [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33450, updated on 7-Aug-2025
Official Symbol
Or23aprovided by FlyBase
Official Full Name
Odorant receptor 23aprovided by FlyBase
Primary source
FLYBASE:FBgn0026395
Locus tag
Dmel_CG9880
See related
AllianceGenome:FB:FBgn0026395
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
23a; 23A.1; AN5; CG9880; Dmel\CG9880; DOR23A.1; dor64; Dor64; DOR64; or23a; OR23a; Or23A.1; Or64
Summary
Enables ionotropic olfactory receptor activity. Involved in sensory perception of smell. Located in dendrite and neuronal cell body. Is expressed in adult olfactory antennal lobe glomerulus; antennal intermediate sensillum ai2; organism subdivision; and sensory neurons. [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
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See Or23a in Genome Data Viewer
Location:
23A2-23A2; 2-7 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2654049..2655462)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2654049..2655462)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Proteasome beta4 subunit-related 1 Neighboring gene Proteasome beta4 subunit-related 2 Neighboring gene TBP-related factor 4 Neighboring gene pseudo

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Olfactory receptor trafficking involves conserved regulatory steps. Gimelbrant AA, et al. J Biol Chem, 2001 Mar 9. PMID 11060288
  2. Convergent projections of Drosophila olfactory neurons to specific glomeruli in the antennal lobe. Gao Q, et al. Nat Neurosci, 2000 Aug. PMID 10903570
  3. Population genomic inferences from sparse high-throughput sequencing of two populations of Drosophila melanogaster. Sackton TB, et al. Genome Biol Evol, 2009 Nov 18. PMID 20333214, Free PMC Article
  4. Farnesol-detecting olfactory neurons in Drosophila. Ronderos DS, et al. J Neurosci, 2014 Mar 12. PMID 24623773, Free PMC Article
  5. Exitron splicing of odor receptor genes in Drosophila. Shang X, et al. Proc Natl Acad Sci U S A, 2024 Mar 26. PMID 38507450, Free PMC Article

See all (68) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The or23a neuron major projected into glomerulu of DL4, DA4 and minor projected into DL5/1.
    Title: Olfactory neurons expressing identified receptor genes project to subsets of glomeruli within the antennal lobe of Drosophila melanogaster.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ionotropic olfactory receptor activity HDA PubMed 
enables ionotropic olfactory receptor activity ISM
Inferred from Sequence Model
more info
 PubMed 
enables odorant binding IEA
Inferred from Electronic Annotation
more info
  
enables odorant binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables olfactory receptor activity NAS
Non-traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in detection of chemical stimulus involved in sensory perception of smell HDA PubMed 
involved_in detection of chemical stimulus involved in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
  
involved_in sensory perception of smell IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in sensory perception of smell NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in dendrite IDA
Inferred from Direct Assay
more info
 PubMed 
located_in dendrite membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
located_in neuronal cell body IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane HDA PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane ISM
Inferred from Sequence Model
more info
 PubMed 
Preferred Names
odorant receptor 23a
Names
CG9880-PA
Or23a-PA
odorant receptor 64
olfactory receptor 23A.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    2654049..2655462
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078734.4 → NP_523458.3  odorant receptor 23a

    See identical proteins and their annotated locations for NP_523458.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P81912
    Related
    FBpp0077382
    Conserved Domains (1) summary
    pfam02949
    Location:59 → 365
    7tm_6; 7tm Odorant receptor
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P81912.1 P81912

Gene LinkOut

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