Or22c Odorant receptor 22c [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Or22cprovided by FlyBase
Official Full Name: Odorant receptor 22cprovided by FlyBase
Primary source: FLYBASE:FBgn0026396
Locus tag: Dmel_CG15377
See related: AllianceGenome:FB:FBgn0026396
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 22c; 22C.1; CG15377; Dmel\CG15377; DOR16; DOR22C.1; Or22C.1
Summary: Predicted to enable ionotropic olfactory receptor activity and odorant binding activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in dendrite membrane. Predicted to be part of cation channel complex. Predicted to be active in plasma membrane. Is expressed in larval antennal lobe glomerulus 22c and larval olfactory receptor neuron Or22c. [provided by Alliance of Genome Resources, Jul 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (2054589..2057967)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (2054589..2057967)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables ionotropic olfactory receptor activity	ISS Inferred from Sequence or Structural Similarity more info
enables odorant binding	IEA Inferred from Electronic Annotation more info
enables odorant binding	ISS Inferred from Sequence or Structural Similarity more info
enables olfactory receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables olfactory receptor activity	IEA Inferred from Electronic Annotation more info
enables olfactory receptor activity	NAS Non-traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
involved_in detection of chemical stimulus involved in sensory perception of smell	IBA Inferred from Biological aspect of Ancestor more info
involved_in detection of chemical stimulus involved in sensory perception of smell	ISS Inferred from Sequence or Structural Similarity more info
involved_in sensory perception of smell	IEA Inferred from Electronic Annotation more info
involved_in sensory perception of smell	NAS Non-traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
part_of cation channel complex	ISS Inferred from Sequence or Structural Similarity more info
located_in dendrite membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	NAS Non-traceable Author Statement more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	ISS Inferred from Sequence or Structural Similarity more info