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IA-2 IA-2 protein tyrosine phosphatase [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33277, updated on 6-May-2021

Summary

Official Symbol
IA-2provided by FlyBase
Official Full Name
IA-2 protein tyrosine phosphataseprovided by FlyBase
Primary source
FLYBASE:FBgn0031294
Locus tag
Dmel_CG31795
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0153538.69; CG11344; CG31795; CG4355; Dmel\CG31795; ia2; IA2; R-PTPX/1A2
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Genomic context

See IA-2 in Genome Data Viewer
Location:
21E3-21E3; 2-1.5 cM
Exon count:
14
Annotation release Status Assembly Chr Location
Release 6.32 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (1008378..1048053, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (1008378..1048053, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44801 Neighboring gene antisense RNA:CR46486 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Star Neighboring gene asteroid

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
IA-2 protein tyrosine phosphatase
Names
CG31795-PC
CG31795-PD
CG31795-PE
IA-2 ortholog
IA-2-PC
IA-2-PD
IA-2-PE
ia2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    1008378..1048053 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_164401.5NP_722672.3  IA-2 protein tyrosine phosphatase, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_722672.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q59E11
    Related
    FBpp0290631, FBtr0301417
    Conserved Domains (3) summary
    smart00194
    Location:9471207
    PTPc; Protein tyrosine phosphatase, catalytic domain
    cd00047
    Location:9821207
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    pfam11548
    Location:695782
    Receptor_IA-2; Protein-tyrosine phosphatase receptor IA-2
  2. NM_134718.6NP_608562.4  IA-2 protein tyrosine phosphatase, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608562.4

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VPV8
    Related
    FBpp0290630, FBtr0301416
    Conserved Domains (3) summary
    smart00194
    Location:9601220
    PTPc; Protein tyrosine phosphatase, catalytic domain
    cd00047
    Location:9951220
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    pfam11548
    Location:708795
    Receptor_IA-2; Protein-tyrosine phosphatase receptor IA-2
  3. NM_001272922.1NP_001259851.1  IA-2 protein tyrosine phosphatase, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259851.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PAZ4
    Related
    FBpp0304559, FBtr0332270
    Conserved Domains (3) summary
    smart00194
    Location:9591219
    PTPc; Protein tyrosine phosphatase, catalytic domain
    cd00047
    Location:9941219
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    pfam11548
    Location:707794
    Receptor_IA-2; Protein-tyrosine phosphatase receptor IA-2
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