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HSPA7 heat shock protein family A (Hsp70) member 7 (pseudogene) [ Homo sapiens (human) ]

Gene ID: 3311, updated on 25-Jan-2022

Summary

Official Symbol
HSPA7provided by HGNC
Official Full Name
heat shock protein family A (Hsp70) member 7 (pseudogene)provided by HGNC
Primary source
HGNC:HGNC:5240
See related
MIM:140556; AllianceGenome:HGNC:5240
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HSP70B
Summary
Predicted to enable several functions, including ATP binding activity; misfolded protein binding activity; and ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including cellular response to unfolded protein; chaperone cofactor-dependent protein refolding; and protein refolding. Located in blood microparticle and extracellular exosome. Colocalizes with COP9 signalosome. [provided by Alliance of Genome Resources, Nov 2021]
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Genomic context

See HSPA7 in Genome Data Viewer
Location:
1q23.3
Exon count:
1
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (161606059..161608551)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (161575849..161578341)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene Fc gamma receptor IIIa Neighboring gene Fc gamma receptor IIc (gene/pseudogene) Neighboring gene tRNA-Leu (anticodon CAA) 6-1 Neighboring gene ribosomal protein S23 pseudogene 9

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Other Names

  • heat shock 70kD protein 7 (HSP70B)
  • heat shock 70kDa protein 7 (HSP70B)

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ATP hydrolysis activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables heat shock protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables misfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables molecular_function ND
No biological Data available
more info
 
enables protein folding chaperone IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ubiquitin protein ligase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in cellular response to unfolded protein IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in chaperone cofactor-dependent protein refolding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein refolding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in blood microparticle HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular exosome HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_024151.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL451067

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    161606059..161608551
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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