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Ser6 Serine protease 6 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33073, updated on 6-Jul-2026
Official Symbol
Ser6provided by FlyBase
Official Full Name
Serine protease 6provided by FlyBase
Primary source
FLYBASE:FBgn0011834
Locus tag
Dmel_CG2071
See related
AllianceGenome:FB:FBgn0011834
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG2071; Dmel\CG2071; SP47
Summary
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See Ser6 in Genome Data Viewer
Location:
19E5-19E5; 1-65 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (20962605..20963505, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (20833632..20834532, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Niemann-Pick type C-1b Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Transcriptome analysis of Drosophila melanogaster laboratory strains of different geographical origin after long-term laboratory maintenance. Zarubin M, et al. Ecol Evol, 2020 Jul. PMID 32760513, Free PMC Article
  2. Pleiotropic effects of Drosophila neuralized on complex behaviors and brain structure. Rollmann SM, et al. Genetics, 2008 Jul. PMID 18562639, Free PMC Article
  3. Genome-wide analysis of genes associated with moderate and high DDT resistance in Drosophila melanogaster. Qiu X, et al. Pest Manag Sci, 2013 Aug. PMID 23371854
  4. Modulation of protease expression by the transcription factor Ptx1/PITX regulates protein quality control during aging. Jiao J, et al. Cell Rep, 2023 Jan 31. PMID 36640359, Free PMC Article
  5. Functional genomic analyses of two morphologically distinct classes of Drosophila sensory neurons: post-mitotic roles of transcription factors in dendritic patterning. Iyer EP, et al. PLoS One, 2013. PMID 23977298, Free PMC Article

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type endopeptidase activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
involved_in proteolysis ISM
Inferred from Sequence Model
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
serine protease 6
Names
CG2071-PA
Ser6-PA
NP_523426.1

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    20962605..20963505 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078702.2 → NP_523426.1  serine protease 6

    See identical proteins and their annotated locations for NP_523426.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7JXW4, Q9VRD0
    Related
    FBpp0076964
    Conserved Domains (2) summary
    smart00020
    Location:31 → 253
    Tryp_SPc; Trypsin-like serine protease
    cd00190
    Location:32 → 256
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q23987 Q23987
Q9VRD0 Q9VRD0

Gene LinkOut

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