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B4galnt4 beta-1,4-N-acetyl-galactosaminyl transferase 4 [ Mus musculus (house mouse) ]

Gene ID: 330671, updated on 5-Mar-2024

Summary

Official Symbol
B4galnt4provided by MGI
Official Full Name
beta-1,4-N-acetyl-galactosaminyl transferase 4provided by MGI
Primary source
MGI:MGI:2652891
See related
Ensembl:ENSMUSG00000055629 AllianceGenome:MGI:2652891
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm1095; NGalNAc-T1; beta4GalNAcT4
Summary
Predicted to enable acetylgalactosaminyltransferase activity. Predicted to be located in Golgi cisterna membrane. Predicted to be integral component of membrane. Is expressed in bronchiole; lung epithelium; metanephros; ureteric tip; and ureteric trunk. Orthologous to human B4GALNT4 (beta-1,4-N-acetyl-galactosaminyltransferase 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in CNS E18 (RPKM 44.9), whole brain E14.5 (RPKM 39.5) and 11 other tissues See more
Orthologs
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Genomic context

See B4galnt4 in Genome Data Viewer
Location:
7 F5; 7 86.32 cM
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (140640891..140652313)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (141060978..141072400)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene interferon induced transmembrane protein 6 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:148234260-148234369 Neighboring gene predicted gene, 39114 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:148258281-148258545 Neighboring gene plakophilin 3 Neighboring gene STARR-positive B cell enhancer ABC_E2255 Neighboring gene single immunoglobulin and toll-interleukin 1 receptor (TIR) domain

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

General gene information

Markers

Clone Names

  • MGC48196

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables acetylgalactosaminyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables acetylgalactosaminyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables acetylgalactosaminyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi cisterna membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1
Names
beta 1,4-N-acetylgalactosaminyltransferase-transferase 4
beta-1,4-N-acetylgalactosaminyltransferase IV
beta1,4-N-acetylgalactosaminyltransferase IV
beta4GalNAc-T4
NP_808565.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177897.4NP_808565.2  N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1

    See identical proteins and their annotated locations for NP_808565.2

    Status: VALIDATED

    Source sequence(s)
    AC109272
    Consensus CDS
    CCDS21998.1
    UniProtKB/Swiss-Prot
    Q766D5, Q8CHV2
    Related
    ENSMUSP00000039758.6, ENSMUST00000048002.7
    Conserved Domains (2) summary
    cl08459
    Location:143277
    PA14; PA14 domain
    cl11394
    Location:7061015
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    140640891..140652313
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)