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Kctd10 potassium channel tetramerisation domain containing 10 [ Mus musculus (house mouse) ]

Gene ID: 330171, updated on 23-Jun-2021

Summary

Official Symbol
Kctd10provided by MGI
Official Full Name
potassium channel tetramerisation domain containing 10provided by MGI
Primary source
MGI:MGI:2141207
See related
Ensembl:ENSMUSG00000001098
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C87062; AW536343; mBACURD3
Expression
Ubiquitous expression in lung adult (RPKM 118.3), colon adult (RPKM 56.8) and 27 other tissues See more
Orthologs
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Genomic context

See Kctd10 in Genome Data Viewer
Location:
5; 5 F
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (114501633..114518566, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (114363572..114380505, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (114813581..114830514, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene forkhead box N4 Neighboring gene VISTA enhancer mm1522 Neighboring gene myosin 1H Neighboring gene ubiquitin protein ligase E3B Neighboring gene microRNA 7027 Neighboring gene methylmalonic aciduria (cobalamin deficiency) cblB type homolog (human)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC11654

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables Notch binding ISO
Inferred from Sequence Orthology
more info
PubMed 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
contributes_to ubiquitin-protein transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of Cul3-RING ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of MKS complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of MKS complex TAS
Traceable Author Statement
more info
PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3
Names
BTB/POZ domain-containing protein KCTD10
potassium channel tetramerization domain-containing 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159941.1NP_001153413.1  BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK147714, AK161199, BB855690, BQ571808
    Consensus CDS
    CCDS51623.1
    UniProtKB/Swiss-Prot
    Q922M3
    UniProtKB/TrEMBL
    F8WGQ9
    Related
    ENSMUSP00000001125.6, ENSMUST00000001125.6
    Conserved Domains (2) summary
    smart00225
    Location:33131
    BTB; Broad-Complex, Tramtrack and Bric a brac
    pfam02214
    Location:34124
    BTB_2; BTB/POZ domain
  2. NM_026145.4NP_080421.2  BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 isoform 2

    See identical proteins and their annotated locations for NP_080421.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the coding region, compared to variant 1, which results in a protein (isoform 2) that is one amino acid shorter than isoform 1.
    Source sequence(s)
    AK147714, AK161199, BB855690
    Consensus CDS
    CCDS19563.1
    UniProtKB/Swiss-Prot
    Q922M3
    Related
    ENSMUSP00000099641.5, ENSMUST00000102581.11
    Conserved Domains (2) summary
    smart00225
    Location:33131
    BTB; Broad-Complex, Tramtrack and Bric a brac
    pfam02214
    Location:34124
    BTB_2; BTB/POZ domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    114501633..114518566 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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