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Fam166b family with sequence similarity 166, member B [ Mus musculus (house mouse) ]

Gene ID: 329831, updated on 26-Sep-2022

Summary

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Official Symbol
Fam166bprovided by MGI
Official Full Name
family with sequence similarity 166, member Bprovided by MGI
Primary source
MGI:MGI:2445194
See related
Ensembl:ENSMUSG00000042788 AllianceGenome:MGI:2445194
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4833436C18Rik
Summary
Is expressed in lung. Orthologous to human FAM166B (family with sequence similarity 166 member B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in ovary adult (RPKM 3.3), stomach adult (RPKM 2.3) and 21 other tissues See more
Orthologs
human all
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Genomic context

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See Fam166b in Genome Data Viewer
Location:
4; 4 A5
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (43427014..43431451, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (43427014..43432131, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene ATPase, class I, type 8B, member 5 Neighboring gene predicted gene, 46850 Neighboring gene RUN and SH3 domain containing 2 Neighboring gene predicted gene, 52698 Neighboring gene testis specific protein kinase 1 Neighboring gene CD72 antigen Neighboring gene suppression inducing transmembrane adaptor 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Stauber M, et al. Dev Biol, 2017 Mar 15. PMID 27914912
  2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (12) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
is_active_in cellular_component ND
No biological Data available
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein FAM166B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001162381.1 → NP_001155853.1  protein FAM166B isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks a segment in the 3' coding region that results in a frameshift, compared to variant 1, and a protein (isoform 2) with a shorter and distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AK029435, AK053208
    Consensus CDS
    CCDS51163.1
    UniProtKB/Swiss-Prot
    A2AIP0
    UniProtKB/TrEMBL
    E9Q4G6
    Related
    ENSMUSP00000127145.3, ENSMUST00000171134.9
    Conserved Domains (1) summary
    pfam10629
    Location:16 → 82
    DUF2475; Protein of unknown function (DUF2475)

  2. NM_001369077.1 → NP_001356006.1  protein FAM166B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL732506
    Consensus CDS
    CCDS89735.1
    UniProtKB/Swiss-Prot
    Q8CDW8
    Related
    ENSMUSP00000103562.4, ENSMUST00000107929.10
    Conserved Domains (1) summary
    pfam10629
    Location:16 → 45
    DUF2475; Protein of unknown function (DUF2475)

  3. NM_177377.5 → NP_796351.2  protein FAM166B isoform 1

    See identical proteins and their annotated locations for NP_796351.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AK029435, AK053208
    Consensus CDS
    CCDS51162.1
    UniProtKB/Swiss-Prot
    A2AIP0
    Related
    ENSMUSP00000058980.4, ENSMUST00000052829.10
    Conserved Domains (1) summary
    pfam10629
    Location:16 → 85
    DUF2475; Protein of unknown function (DUF2475)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    43427014..43431451 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006538011.5 → XP_006538074.1  protein FAM166B isoform X1

    See identical proteins and their annotated locations for XP_006538074.1

    UniProtKB/Swiss-Prot
    A2AIP0
    Conserved Domains (1) summary
    pfam10629
    Location:16 → 85
    DUF2475; Protein of unknown function (DUF2475)

  2. XM_006538012.5 → XP_006538075.1  protein FAM166B isoform X3

    See identical proteins and their annotated locations for XP_006538075.1

    UniProtKB/Swiss-Prot
    A2AIP0, Q8CDW8
    Conserved Domains (1) summary
    pfam10629
    Location:16 → 45
    DUF2475; Protein of unknown function (DUF2475)

  3. XM_011250054.4 → XP_011248356.1  protein FAM166B isoform X2

    Conserved Domains (1) summary
    pfam10629
    Location:16 → 85
    DUF2475; Protein of unknown function (DUF2475)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A2AIP0.1 GenPept UniProtKB/Swiss-Prot:A2AIP0

Gene LinkOut

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