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Ankrd44 ankyrin repeat domain 44 [ Mus musculus (house mouse) ]

Gene ID: 329154, updated on 8-Nov-2022

Summary

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Official Symbol
Ankrd44provided by MGI
Official Full Name
ankyrin repeat domain 44provided by MGI
Primary source
MGI:MGI:3045243
See related
Ensembl:ENSMUSG00000052331 AllianceGenome:MGI:3045243
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
PP6-ARS-B; A130096K20; 4930444A19Rik; E130014H08Rik
Summary
Orthologous to human ANKRD44 (ankyrin repeat domain 44). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in thymus adult (RPKM 10.4), lung adult (RPKM 10.2) and 24 other tissues See more
Orthologs
human all
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Genomic context

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See Ankrd44 in Genome Data Viewer
Location:
1; 1 C1.2
Exon count:
30
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (54684499..54968142, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (54645340..54928983, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene post-GPI attachment to proteins 1 Neighboring gene predicted gene, 51623 Neighboring gene predicted gene, 19637 Neighboring gene RIKEN cDNA 4930444A19 gene Neighboring gene splicing factor 3b, subunit 1 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene coenzyme Q10B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. ATG5 is required for B cell polarization and presentation of particulate antigens. Arbogast F, et al. Autophagy, 2019 Feb. PMID 30196744, Free PMC Article
  2. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Zhang T, et al. Sci Rep, 2017 Apr 5. PMID 28378742, Free PMC Article
  3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (12) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B
Names
ankyrin repeat domain-containing protein 44
serine/threonine-protein phosphatase 6 regulatory subunit ARS-B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081433.3 → NP_001074902.2  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B

    See identical proteins and their annotated locations for NP_001074902.2

    Status: VALIDATED

    Source sequence(s)
    AC151572, AC160472, AC166111, BF461794
    Consensus CDS
    CCDS35566.2
    UniProtKB/Swiss-Prot
    B2RXR6, B7ZWK8
    Related
    ENSMUSP00000137616.2, ENSMUST00000179030.8
    Conserved Domains (6) summary
    cd00204
    Location:134 → 259
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00023
    Location:272 → 304
    Ank; Ankyrin repeat
    pfam12796
    Location:177 → 269
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:672 → 723
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:722 → 779
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:140 → 170
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    54684499..54968142 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030254997.1 → XP_030110857.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X9

    Related
    ENSMUSP00000136802.2, ENSMUST00000178226.3
    Conserved Domains (2) summary
    PHA03095
    Location:14 → 287
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:68 → 98
    ANK; ANK repeat [structural motif]

  2. XM_030254994.1 → XP_030110854.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X6

    Conserved Domains (2) summary
    PHA03095
    Location:14 → 287
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:68 → 98
    ANK; ANK repeat [structural motif]

  3. XM_006496071.4 → XP_006496134.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X2

    Conserved Domains (3) summary
    PHA03095
    Location:86 → 359
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:140 → 170
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:12 → 104
    Ank_2; Ankyrin repeats (3 copies)

  4. XM_006496073.4 → XP_006496136.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X5

    UniProtKB/TrEMBL
    E9QNQ2
    Related
    ENSMUSP00000040327.10, ENSMUST00000044359.16
    Conserved Domains (3) summary
    PHA03095
    Location:86 → 359
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:140 → 170
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:12 → 104
    Ank_2; Ankyrin repeats (3 copies)

  5. XM_006496070.4 → XP_006496133.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X1

    Conserved Domains (3) summary
    PHA03095
    Location:86 → 359
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:140 → 170
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:12 → 104
    Ank_2; Ankyrin repeats (3 copies)

  6. XM_030254996.1 → XP_030110856.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X7

    Conserved Domains (2) summary
    PHA03095
    Location:14 → 287
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:68 → 98
    ANK; ANK repeat [structural motif]

  7. XM_036165753.1 → XP_036021646.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X8

    Conserved Domains (3) summary
    PHA03095
    Location:61 → 334
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:115 → 145
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:2 → 79
    Ank_2; Ankyrin repeats (3 copies)

  8. XM_030254992.1 → XP_030110852.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X4

    Conserved Domains (3) summary
    PHA03095
    Location:61 → 334
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:115 → 145
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:2 → 79
    Ank_2; Ankyrin repeats (3 copies)

  9. XM_011238538.3 → XP_011236840.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X3

    Conserved Domains (3) summary
    PHA03095
    Location:61 → 334
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:115 → 145
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:2 → 79
    Ank_2; Ankyrin repeats (3 copies)

  10. XM_030254995.2 → XP_030110855.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X6

    Conserved Domains (2) summary
    PHA03095
    Location:14 → 287
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:68 → 98
    ANK; ANK repeat [structural motif]

  11. XM_030254991.2 → XP_030110851.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X3

    Conserved Domains (3) summary
    PHA03095
    Location:61 → 334
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:115 → 145
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:2 → 79
    Ank_2; Ankyrin repeats (3 copies)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B2RXR6.1 GenPept UniProtKB/Swiss-Prot:B2RXR6

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