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Rab26 RAB26, member RAS oncogene family [ Mus musculus (house mouse) ]

Gene ID: 328778, updated on 11-Apr-2024

Summary

Official Symbol
Rab26provided by MGI
Official Full Name
RAB26, member RAS oncogene familyprovided by MGI
Primary source
MGI:MGI:2443284
See related
Ensembl:ENSMUSG00000079657 AllianceGenome:MGI:2443284
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
A830020M03Rik
Summary
Predicted to enable GMP binding activity and GTP binding activity. Predicted to be involved in several processes, including Golgi to plasma membrane protein transport; exocrine system development; and regulation of protein catabolic process at presynapse, modulating synaptic transmission. Predicted to act upstream of or within protein transport. Located in secretory granule membrane. Orthologous to human RAB26 (RAB26, member RAS oncogene family). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in frontal lobe adult (RPKM 24.6), cortex adult (RPKM 21.7) and 4 other tissues See more
Orthologs
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Genomic context

Location:
17 A3.3; 17 12.4 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (24748038..24752696, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (24529054..24533747, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene CASK interacting protein 1 Neighboring gene TNF receptor-associated factor 7 Neighboring gene STARR-positive B cell enhancer ABC_E33 Neighboring gene RAB26, member RAS oncogene family, opposite strand Neighboring gene small nucleolar RNA, C/D box 60 Neighboring gene predicted gene, 33508 Neighboring gene STARR-positive B cell enhancer ABC_E1189 Neighboring gene predicted gene, 57643 Neighboring gene polycystin 1, transient receptor potential channel interacting

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables GMP binding ISO
Inferred from Sequence Orthology
more info
 
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables GTP binding ISO
Inferred from Sequence Orthology
more info
 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in Golgi to plasma membrane protein transport ISO
Inferred from Sequence Orthology
more info
 
involved_in exocrine system development ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in regulated exocytosis ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of exocytosis ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation protein catabolic process at presynapse ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in Golgi membrane ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in secretory granule membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in synaptic vesicle membrane ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177375.2NP_796349.1  ras-related protein Rab-26

    See identical proteins and their annotated locations for NP_796349.1

    Status: VALIDATED

    Source sequence(s)
    AC132367
    Consensus CDS
    CCDS50016.1
    UniProtKB/Swiss-Prot
    Q504M8
    UniProtKB/TrEMBL
    H3BLG3, Q0PD29, Q148R0
    Related
    ENSMUSP00000046089.10, ENSMUST00000035797.16
    Conserved Domains (2) summary
    smart00175
    Location:68232
    RAB; Rab subfamily of small GTPases
    cd04112
    Location:68258
    Rab26; Rab GTPase family 26 (Rab26)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    24748038..24752696 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)