Nup35 Nucleoporin 35kDa [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Nup35provided by FlyBase
Official Full Name: Nucleoporin 35kDaprovided by FlyBase
Primary source: FLYBASE:FBgn0030943
Locus tag: Dmel_CG6540
See related: AllianceGenome:FB:FBgn0030943
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG6540; Dmel\CG6540; nup35; Nup53
Summary: Predicted to enable phospholipid binding activity and single-stranded DNA binding activity. Predicted to be a structural constituent of nuclear pore. Predicted to be involved in NLS-bearing protein import into nucleus; nuclear pore organization; and regulation of transcription, DNA-templated. Predicted to be located in nuclear membrane. Predicted to be part of nuclear pore central transport channel and nuclear pore nuclear basket. Is expressed in several structures, including embryonic brain; embryonic/larval visceral muscle cell; extended germ band embryo; germline cell; and gonad. Orthologous to human NUP35 (nucleoporin 35). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (18648182..18649489)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (18542215..18543522)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables phospholipid binding	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of nuclear pore	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of nuclear pore	IEA Inferred from Electronic Annotation more info
enables structural constituent of nuclear pore	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in NLS-bearing protein import into nucleus	IBA Inferred from Biological aspect of Ancestor more info
involved_in nuclear pore organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in nuclear pore organization	ISS Inferred from Sequence or Structural Similarity more info
involved_in nucleocytoplasmic transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nuclear membrane	IEA Inferred from Electronic Annotation more info
part_of nuclear pore central transport channel	IBA Inferred from Biological aspect of Ancestor more info
part_of nuclear pore central transport channel	ISS Inferred from Sequence or Structural Similarity more info
part_of nuclear pore nuclear basket	IBA Inferred from Biological aspect of Ancestor more info

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The following sections contain reference sequences that belong to a specific genome build. Explain