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brd3b bromodomain containing 3b [ Danio rerio (zebrafish) ]

Gene ID: 327108, updated on 4-Jan-2025

Summary

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Official Symbol
brd3bprovided by ZNC
Official Full Name
bromodomain containing 3bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-5316
See related
Ensembl:ENSDARG00000100129 AllianceGenome:ZFIN:ZDB-GENE-030131-5316
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fa28f05; zgc:77289; wu:fa28f05; wu:fc56a11; wu:fj66d12
Summary
Orthologous to human BRD3 (bromodomain containing 3). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
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Genomic context

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See brd3b in Genome Data Viewer
Location:
chromosome: 5
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (64412005..64454466, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (63730841..63773297, complement)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene endothelial differentiation-related factor 1 Neighboring gene BRD3 opposite strand Neighboring gene uncharacterized LOC137495653 Neighboring gene retinoid x receptor, alpha b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Evolutionary history of the ABCB2 genomic region in teleosts. Palti Y, et al. Dev Comp Immunol, 2007. PMID 17055577
  2. Bromodomain and extraterminal (BET) proteins regulate biliary-driven liver regeneration. Ko S, et al. J Hepatol, 2016 Feb. PMID 26505118, Free PMC Article
  3. Mammalian Target of Rapamycin Complex 1 Signaling Is Required for the Dedifferentiation From Biliary Cell to Bipotential Progenitor Cell in Zebrafish Liver Regeneration. He J, et al. Hepatology, 2019 Dec. PMID 31136010
  4. Characterization of retinoid-X receptor genes rxra, rxrba, rxrbb and rxrg during zebrafish development. Tallafuss A, et al. Gene Expr Patterns, 2006 Jun. PMID 16448862
  5. CRISPR gRNA phenotypic screening in zebrafish reveals pro-regenerative genes in spinal cord injury. Keatinge M, et al. PLoS Genet, 2021 Apr. PMID 33914736, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

General protein information

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Preferred Names
bromodomain-containing protein 3b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212702.1 → NP_997867.1  bromodomain-containing protein 3b

    See identical proteins and their annotated locations for NP_997867.1

    Status: PROVISIONAL

    Source sequence(s)
    BC065949
    UniProtKB/TrEMBL
    Q6NZW1
    Related
    ENSDARP00000129878.1, ENSDART00000168030.2
    Conserved Domains (3) summary
    cd05497
    Location:30 → 136
    Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    cd05498
    Location:294 → 395
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:551 → 615
    BET; Bromodomain extra-terminal - transcription regulation

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    64412005..64454466 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068221103.1 → XP_068077204.1  bromodomain-containing protein 3b isoform X5

  2. XM_005165594.5 → XP_005165651.2  bromodomain-containing protein 3b isoform X2

    UniProtKB/TrEMBL
    A0A8M2BCY3
    Conserved Domains (3) summary
    cd05497
    Location:30 → 136
    Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    cd05498
    Location:293 → 394
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:573 → 637
    BET; Bromodomain extra-terminal - transcription regulation

  3. XM_068221106.1 → XP_068077207.1  bromodomain-containing protein 3b isoform X8

  4. XM_009301938.4 → XP_009300213.1  bromodomain-containing protein 3b isoform X4

    UniProtKB/TrEMBL
    A0A8M3ASX2
    Conserved Domains (3) summary
    cd05497
    Location:30 → 136
    Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    cd05498
    Location:294 → 395
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:551 → 615
    BET; Bromodomain extra-terminal - transcription regulation

  5. XM_005165595.5 → XP_005165652.2  bromodomain-containing protein 3b isoform X3

    UniProtKB/TrEMBL
    A0A8M2BCV5
    Conserved Domains (3) summary
    cd05497
    Location:30 → 136
    Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    cd05498
    Location:294 → 395
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:551 → 615
    BET; Bromodomain extra-terminal - transcription regulation

  6. XM_009301940.4 → XP_009300215.1  bromodomain-containing protein 3b isoform X7

    UniProtKB/TrEMBL
    A0A8M3B2Y4
    Related
    ENSDARP00000141933.1, ENSDART00000172321.2
    Conserved Domains (3) summary
    cd05497
    Location:30 → 136
    Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    cd05498
    Location:294 → 395
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:574 → 638
    BET; Bromodomain extra-terminal - transcription regulation

  7. XM_068221105.1 → XP_068077206.1  bromodomain-containing protein 3b isoform X6

  8. XM_009301936.4 → XP_009300211.1  bromodomain-containing protein 3b isoform X1

    See identical proteins and their annotated locations for XP_009300211.1

    UniProtKB/TrEMBL
    A0A8M2BCV6
    Conserved Domains (3) summary
    cd05497
    Location:30 → 136
    Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    cd05498
    Location:294 → 395
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:574 → 638
    BET; Bromodomain extra-terminal - transcription regulation

  9. XM_068221104.1 → XP_068077205.1  bromodomain-containing protein 3b isoform X5

  10. XM_068221101.1 → XP_068077202.1  bromodomain-containing protein 3b isoform X2

    UniProtKB/TrEMBL
    A0A8M2BCY3

  11. XM_068221107.1 → XP_068077208.1  bromodomain-containing protein 3b isoform X9

  12. XM_068221102.1 → XP_068077203.1  bromodomain-containing protein 3b isoform X3

    UniProtKB/TrEMBL
    A0A8M2BCV5

  13. XM_005165593.5 → XP_005165650.2  bromodomain-containing protein 3b isoform X1

    See identical proteins and their annotated locations for XP_005165650.2

    UniProtKB/TrEMBL
    A0A8M2BCV6
    Conserved Domains (3) summary
    cd05497
    Location:30 → 136
    Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    cd05498
    Location:294 → 395
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:574 → 638
    BET; Bromodomain extra-terminal - transcription regulation
Nucleotide Protein Strain
Heading Accession and Version

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