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CG32379 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 326211, updated on 5-Jan-2023

Summary

Official Symbol
CG32379provided by FlyBase
Primary source
FLYBASE:FBgn0052379
Locus tag
Dmel_CG32379
See related
AllianceGenome:FB:FBgn0052379
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG18415; Dmel\CG32379
Summary
Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in chronic kidney disease; familial febrile seizures 11; and familial temporal lobe epilepsy 5. Orthologous to several human genes including CPA1 (carboxypeptidase A1); CPA2 (carboxypeptidase A2); and CPA3 (carboxypeptidase A3). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See CG32379 in Genome Data Viewer
Location:
65F11-65F11; 3-20 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.46 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (7396355..7398208)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (7389455..7391308)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables metallocarboxypeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metallocarboxypeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
uncharacterized protein
Names
CG32379-PB
NP_729252.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    7396355..7398208
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_168213.3NP_729252.2  uncharacterized protein Dmel_CG32379 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_729252.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VS65
    Related
    FBpp0271927, FBtr0273419
    Conserved Domains (1) summary
    cd03860
    Location:44338
    M14_CP_A-B_like; Peptidase M14 carboxypeptidase subfamily A/B-like