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Slc25A46a Solute carrier family 25 member 46a [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32564, updated on 4-Jan-2025

Summary

Official Symbol
Slc25A46aprovided by FlyBase
Official Full Name
Solute carrier family 25 member 46aprovided by FlyBase
Primary source
FLYBASE:FBgn0030717
Locus tag
Dmel_CG8931
See related
AllianceGenome:FB:FBgn0030717
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG8931; Dmel\CG8931; dSLC25A46a; SLC25A46a
Summary
Predicted to be involved in mitochondrial fission. Predicted to be active in mitochondrial outer membrane. Is expressed in adult head and organism. Used to study Charcot-Marie-Tooth disease type 6. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 1E. Orthologous to human SLC25A46 (solute carrier family 25 member 46). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See Slc25A46a in Genome Data Viewer
Location:
14A5-14A5; 1-52 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15983772..15985405)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15877805..15879438)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene centrosomal protein 164 Neighboring gene NADH dehydrogenase (ubiquinone) 20 kDa subunit Neighboring gene uncharacterized protein Neighboring gene eukaryotic translation initiation factor 5

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in mitochondrial fission IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in mitochondrial membrane fission IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in mitochondrial outer membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial outer membrane NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
solute carrier family 25 member 46a
Names
CG8931-PA
Slc25A46a-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    15983772..15985405
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132868.5NP_573096.1  solute carrier family 25 member 46a [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_573096.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VXK8
    Related
    FBpp0073939
    Conserved Domains (1) summary
    pfam00153
    Location:277360
    Mito_carr; Mitochondrial carrier protein