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bhlhe40 basic helix-loop-helix family, member e40 [ Danio rerio (zebrafish) ]

Gene ID: 324413, updated on 3-Oct-2019

Summary

Official Symbol
bhlhe40provided by ZNC
Official Full Name
basic helix-loop-helix family, member e40provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-3133
See related
Ensembl:ENSDARG00000004060
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
DEC1; bhlhb2; zgc:76913; wu:fc28a06; wu:fm54h07
Orthologs

Genomic context

See bhlhe40 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (35759652..35763257, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (35497669..35501274, complement)
103 previous assembly Zv9 (GCF_000002035.4) 11 NC_007122.5 (36600441..36604046, complement)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb Neighboring gene ADP-ribosylation factor-like 8Bb Neighboring gene inositol 1,4,5-trisphosphate receptor, type 1b Neighboring gene SET domain and mariner transposase fusion gene

Genomic regions, transcripts, and products

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription repressor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
anterior/posterior pattern specification IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
circadian regulation of gene expression IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
circadian regulation of gene expression IDA
Inferred from Direct Assay
more info
PubMed 
locomotor rhythm IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
regulation of neurogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
class E basic helix-loop-helix protein 40
Names
bHLH protein DEC1
basic helix-loop-helix domain containing, class B, 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212679.2NP_997844.2  class E basic helix-loop-helix protein 40

    See identical proteins and their annotated locations for NP_997844.2

    Status: PROVISIONAL

    Source sequence(s)
    AY652763
    UniProtKB/TrEMBL
    Q0D311
    Related
    ENSDARP00000023917.4, ENSDART00000026017.6
    Conserved Domains (2) summary
    cd00083
    Location:51109
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam07527
    Location:139177
    Hairy_orange; Hairy Orange

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    35759652..35763257 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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