tia1l cytotoxic granule-associated RNA binding protein 1, like [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: tia1lprovided by ZNC
Official Full Name: cytotoxic granule-associated RNA binding protein 1, likeprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-2167
See related: Ensembl:ENSDARG00000026476 AllianceGenome:ZFIN:ZDB-GENE-030131-2167
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: TIA1; fb98f09; zgc:55893; zgc:76917; wu:fb98f09
Summary: Predicted to enable RNA binding activity. [provided by Alliance of Genome Resources, Jul 2025]
Orthologs: all
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Genomic context

Location:: chromosome: 5

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2025_04	current	GRCz12tu (GCF_049306965.1)	5	NC_133180.1 (25168188..25175292, complement)
RS_2024_08	previous assembly	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (24510619..24517700, complement)

Chromosome 5 - NC_133180.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb54a07.y1 (e-PCR)
- UniSTS:190693

fb98f09.x1 (e-PCR)
- UniSTS:191977

fb98f09.x1 (e-PCR)
- UniSTS:191978

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cytotoxic granule-associated RNA binding protein 1, like

Names: TIA1 cytotoxic granule-associated RNA binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200182.2 → NP_956476.1 cytotoxic granule-associated RNA binding protein 1, like

See identical proteins and their annotated locations for NP_956476.1

Status: PROVISIONAL

Source sequence(s)

BC066734

UniProtKB/TrEMBL

F6P2U6, Q6NY54, Q7ZVM6

Related

ENSDARP00000018009.6, ENSDART00000003957.7

Conserved Domains (4) summary

cd12618
Location:96 → 175

RRM2_TIA1; RNA recognition motif 2 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins

cd12620
Location:206 → 278

RRM3_TIAR; RNA recognition motif 3 in nucleolysin TIAR and similar proteins

TIGR01661
Location:7 → 272

ELAV_HUD_SF; ELAV/HuD family splicing factor

cl17169
Location:10 → 90

RRM_SF; RNA recognition motif (RRM) superfamily