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CG42237 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32261, updated on 4-Jan-2025

Summary

Official Symbol
CG42237provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0250862
Locus tag
Dmel_CG42237
See related
AllianceGenome:FB:FBgn0250862
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
C133; CG4346; Dmel\CG42237; PLA2
Old locus tag
Dmel_CG4346
Summary
Predicted to enable calcium-dependent phospholipase A2 activity. Predicted to be involved in arachidonate secretion and phospholipid metabolic process. Is expressed in adult head and organism. Orthologous to human PROCA1 (protein interacting with cyclin A1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See CG42237 in Genome Data Viewer
Location:
11E1-11E1; 1-42 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (13115131..13123066)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (13009164..13017099)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Chondroitin polymerizing factor Neighboring gene Ferritin 3 heavy chain homologue Neighboring gene uncharacterized protein Neighboring gene small non-coding RNA 204 Neighboring gene uncharacterized protein Neighboring gene Major Facilitator Superfamily Transporter 10

Genomic regions, transcripts, and products

General protein information

Preferred Names
uncharacterized protein
Names
CG42237-PA
CG42237-PB
phospholipase A2
NP_001285185.1
NP_572855.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    13115131..13123066
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298256.1NP_001285185.1  uncharacterized protein Dmel_CG42237, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285185.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    X2JBI9
    Conserved Domains (1) summary
    cd04704
    Location:200294
    PLA2_bee_venom_like; PLA2_bee_venom_like: A sub-family of Phospholipase A2, similar to bee venom PLA2. PLA2 is a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. Enzymatically active PLA2 cleaves the sn-2 position of the ...
  2. NM_132627.2NP_572855.1  uncharacterized protein Dmel_CG42237, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572855.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VYG9
    Related
    FBpp0073553
    Conserved Domains (1) summary
    cd04704
    Location:254348
    PLA2_bee_venom_like; PLA2_bee_venom_like: A sub-family of Phospholipase A2, similar to bee venom PLA2. PLA2 is a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. Enzymatically active PLA2 cleaves the sn-2 position of the ...