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fne found in neurons [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32245, updated on 8-Feb-2025

Summary

Official Symbol
fneprovided by FlyBase
Official Full Name
found in neuronsprovided by FlyBase
Primary source
FLYBASE:FBgn0086675
Locus tag
Dmel_CG4396
See related
AllianceGenome:FB:FBgn0086675
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:HL02010; BcDNA:RE25290; BEST:HL02010; cg4396; CG4396; CR32646; Dmel\CG4396; Fne; FNE; lincRNA.985; MRE28
Old locus tag
CR32646; Dmel_CR32646
Summary
Enables poly(U) RNA binding activity. Involved in male courtship behavior and regulation of mRNA processing. Located in cytoplasm. Is active in cytoplasmic ribonucleoprotein granule. Is expressed in adult brain cell body rind; adult head; and organism. Orthologous to several human genes including ELAVL2 (ELAV like RNA binding protein 2). [provided by Alliance of Genome Resources, Feb 2025]
Orthologs
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Genomic context

See fne in Genome Data Viewer
Location:
11D3-11D4; 1-41 cM
Exon count:
11
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (12917477..12950417)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (12811510..12844450)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45625 Neighboring gene long non-coding RNA:CR45626 Neighboring gene hector Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables mRNA binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables poly(U) RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in male courtship behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of RNA metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of mRNA processing IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytoplasmic ribonucleoprotein granule IDA
Inferred from Direct Assay
more info
PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
found in neurons
Names
CG4396-PA
CG4396-PB
CG4396-PC
CG4396-PD
CG4396-PE
CG4396-PG
CG4396-PH
CG4396-PI
CG4396-PJ
CG4396-PK
CG4396-PL
CR32646
fne-PA
fne-PB
fne-PC
fne-PD
fne-PE
fne-PG
fne-PH
fne-PI
fne-PJ
fne-PK
fne-PL

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    12917477..12950417
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001258718.3NP_001245647.1  found in neurons, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245647.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1NZB4
    Conserved Domains (1) summary
    TIGR01661
    Location:23351
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  2. NM_001258717.1NP_001245646.1  found in neurons, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245646.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9NGV0, Q9VYI0
    Conserved Domains (1) summary
    TIGR01661
    Location:23354
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  3. NM_001258719.2NP_001245648.1  found in neurons, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245648.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9NGV0, Q9VYI0
    Conserved Domains (1) summary
    TIGR01661
    Location:23354
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  4. NM_001414105.1NP_001401059.1  found in neurons, isoform L [Drosophila melanogaster]

    Status: REVIEWED

  5. NM_001414104.1NP_001401058.1  found in neurons, isoform K [Drosophila melanogaster]

    Status: REVIEWED

  6. NM_001258720.3NP_001245649.2  found in neurons, isoform I [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245649.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1NZB4
    Conserved Domains (1) summary
    TIGR01661
    Location:23351
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  7. NM_001272569.1NP_001259498.1  found in neurons, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259498.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9NGV0, Q9VYI0
    Conserved Domains (1) summary
    TIGR01661
    Location:23354
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  8. NM_001103495.5NP_001096965.1  found in neurons, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001096965.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9NGV0, Q9VYI0
    Conserved Domains (1) summary
    TIGR01661
    Location:23354
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  9. NM_132614.6NP_572842.1  found in neurons, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572842.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9NGV0, Q9VYI0
    Related
    FBpp0073543
    Conserved Domains (1) summary
    TIGR01661
    Location:23354
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  10. NM_001272568.2NP_001259497.1  found in neurons, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259497.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9NGV0, Q9VYI0
    Conserved Domains (1) summary
    TIGR01661
    Location:23354
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  11. NM_001298244.1NP_001285173.1  found in neurons, isoform J [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285173.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1NZB4
    Conserved Domains (1) summary
    TIGR01661
    Location:23351
    ELAV_HUD_SF; ELAV/HuD family splicing factor