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ubxn1 UBX domain protein 1 [ Danio rerio (zebrafish) ]

Gene ID: 322073, updated on 27-Mar-2024

Summary

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Official Symbol
ubxn1provided by ZNC
Official Full Name
UBX domain protein 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-792
See related
Ensembl:ENSDARG00000090309 AllianceGenome:ZFIN:ZDB-GENE-030131-792
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fb49a05; zgc:77531; wu:fb49a05
Summary
Predicted to enable K6-linked polyubiquitin modification-dependent protein binding activity. Predicted to be involved in negative regulation of proteasomal ubiquitin-dependent protein catabolic process and negative regulation of protein ubiquitination. Predicted to be located in cytoplasm. Orthologous to human UBXN1 (UBX domain protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 14
Exon count:
9
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (45471709..45482615)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (46484417..46495313)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene microtubule-associated protein 1 light chain 3 gamma, like Neighboring gene EH-domain containing 1a Neighboring gene si:ch211-114c17.1 Neighboring gene glucosidase II alpha subunit b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Protein palmitoylation activate zygotic gene expression during the maternal-to-zygotic transition. Du Z, et al. Biochem Biophys Res Commun, 2016 Jun 24. PMID 27235108
  2. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables K48-linked polyubiquitin modification-dependent protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables K6-linked polyubiquitin modification-dependent protein binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in negative regulation of proteasomal ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of proteasomal ubiquitin-dependent protein catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in negative regulation of protein K48-linked deubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of protein ubiquitination ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
UBX domain-containing protein 1
Names
SAPK substrate protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212607.1 → NP_997772.1  UBX domain-containing protein 1

    See identical proteins and their annotated locations for NP_997772.1

    Status: PROVISIONAL

    Source sequence(s)
    BC067166
    UniProtKB/Swiss-Prot
    Q6NXA9
    Related
    ENSDARP00000108064.1, ENSDART00000126979.4
    Conserved Domains (2) summary
    cd01772
    Location:215 → 293
    SAKS1_UBX; SAKS1-like UBX domain
    cd14302
    Location:5 → 45
    UBA_UBXN1; UBA domain found in UBX domain-containing protein 1 (UBXN1) and similar proteins

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    45471709..45482615
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017358985.2 → XP_017214474.1  UBX domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M6Z444
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6NXA9.1 GenPept UniProtKB/Swiss-Prot:Q6NXA9

Gene LinkOut

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