ywhae1 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ywhae1provided by ZNC
Official Full Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-779
See related: Ensembl:ENSDARG00000006399
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as: ywhae; fe38c12; zgc:55377; zgc:77062; wu:fb48f06; wu:fe38c12; wu:fi22e10
Orthologs: human mouse all

Genomic context

Location:: chromosome: 15

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	15	NC_007126.7 (24746440..24755108)
105	previous assembly	GRCz10 (GCF_000002035.5)	15	NC_007126.6 (24811175..24819843)
103	previous assembly	Zv9 (GCF_000002035.4)	15	NC_007126.5 (24099988..24108656)

Chromosome 15 - NC_007126.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Submit: New GeneRIF Correction

Variation

Go to the top of the page Help

Pathways from BioSystems

Go to the top of the page Help

AURKA Activation by TPX2, organism-specific biosystem (from REACTOME)
AURKA Activation by TPX2, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Activation of BAD and translocation to mitochondria, organism-specific biosystem (from REACTOME)
Activation of BAD and translocation to mitochondria, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Activation of BH3-only proteins, organism-specific biosystem (from REACTOME)
Activation of BH3-only proteins, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem (from WikiPathways)
Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem
Alpha6-Beta4 Integrin Signaling Pathway
Anchoring of the basal body to the plasma membrane, organism-specific biosystem (from REACTOME)
Anchoring of the basal body to the plasma membrane, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Apoptosis, organism-specific biosystem (from REACTOME)
Apoptosis, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Calcium Regulation in the Cardiac Cell, organism-specific biosystem (from WikiPathways)
Calcium Regulation in the Cardiac Cell, organism-specific biosystemCalcium is a common signaling mechanism, as once it enters the cytoplasm it exerts allosteric regulatory affects on many enzymes and proteins. Calcium can act in signal transduction after influx resu...
Cell Cycle, organism-specific biosystem (from REACTOME)
Cell Cycle, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Cell Cycle, Mitotic, organism-specific biosystem (from REACTOME)
Cell Cycle, Mitotic, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Cell cycle, organism-specific biosystem (from KEGG)
Cell cycle, organism-specific biosystemMitotic cell cycle progression is accomplished through a reproducible sequence of events, DNA replication (S phase) and mitosis (M phase) separated temporally by gaps known as G1 and G2 phases. Cycli...
Cell cycle, conserved biosystem (from KEGG)
Cell cycle, conserved biosystemMitotic cell cycle progression is accomplished through a reproducible sequence of events, DNA replication (S phase) and mitosis (M phase) separated temporally by gaps known as G1 and G2 phases. Cycli...
Cellular response to heat stress, organism-specific biosystem (from REACTOME)
Cellular response to heat stress, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Cellular responses to stress, organism-specific biosystem (from REACTOME)
Cellular responses to stress, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Centrosome maturation, organism-specific biosystem (from REACTOME)
Centrosome maturation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Cilium Assembly, organism-specific biosystem (from REACTOME)
Cilium Assembly, organism-specific biosystemcomputationally inferred pathway (not manually curated)
G2/M Transition, organism-specific biosystem (from REACTOME)
G2/M Transition, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Gene Expression, organism-specific biosystem (from REACTOME)
Gene Expression, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Generic Transcription Pathway, organism-specific biosystem (from REACTOME)
Generic Transcription Pathway, organism-specific biosystemcomputationally inferred pathway (not manually curated)
HSF1 activation, organism-specific biosystem (from REACTOME)
HSF1 activation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Intrinsic Pathway for Apoptosis, organism-specific biosystem (from REACTOME)
Intrinsic Pathway for Apoptosis, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Loss of Nlp from mitotic centrosomes, organism-specific biosystem (from REACTOME)
Loss of Nlp from mitotic centrosomes, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Loss of proteins required for interphase microtubule organization from the centrosome, organism-specific biosystem (from REACTOME)
Loss of proteins required for interphase microtubule organization from the centrosome, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Membrane Trafficking, organism-specific biosystem (from REACTOME)
Membrane Trafficking, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Mitotic G2-G2/M phases, organism-specific biosystem (from REACTOME)
Mitotic G2-G2/M phases, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Oocyte meiosis, organism-specific biosystem (from KEGG)
Oocyte meiosis, organism-specific biosystemDuring meiosis, a single round of DNA replication is followed by two rounds of chromosome segregation, called meiosis I and meiosis II. At meiosis I, homologous chromosomes recombine and then segrega...
Oocyte meiosis, conserved biosystem (from KEGG)
Oocyte meiosis, conserved biosystemDuring meiosis, a single round of DNA replication is followed by two rounds of chromosome segregation, called meiosis I and meiosis II. At meiosis I, homologous chromosomes recombine and then segrega...
Organelle biogenesis and maintenance, organism-specific biosystem (from REACTOME)
Organelle biogenesis and maintenance, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Programmed Cell Death, organism-specific biosystem (from REACTOME)
Programmed Cell Death, organism-specific biosystemcomputationally inferred pathway (not manually curated)
RAB GEFs exchange GTP for GDP on RABs, organism-specific biosystem (from REACTOME)
RAB GEFs exchange GTP for GDP on RABs, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Recruitment of mitotic centrosome proteins and complexes, organism-specific biosystem (from REACTOME)
Recruitment of mitotic centrosome proteins and complexes, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Regulation of HSF1-mediated heat shock response, organism-specific biosystem (from REACTOME)
Regulation of HSF1-mediated heat shock response, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Regulation of PLK1 Activity at G2/M Transition, organism-specific biosystem (from REACTOME)
Regulation of PLK1 Activity at G2/M Transition, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Signal Transduction, organism-specific biosystem (from REACTOME)
Signal Transduction, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Signaling by Hippo, organism-specific biosystem (from REACTOME)
Signaling by Hippo, organism-specific biosystemcomputationally inferred pathway (not manually curated)
TNF-alpha NF-kB Signaling Pathway, organism-specific biosystem (from WikiPathways)
TNF-alpha NF-kB Signaling Pathway, organism-specific biosystem
TNF-alpha NF-kB Signaling Pathway
TP53 Regulates Metabolic Genes, organism-specific biosystem (from REACTOME)
TP53 Regulates Metabolic Genes, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Transcriptional Regulation by TP53, organism-specific biosystem (from REACTOME)
Transcriptional Regulation by TP53, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Translocation of GLUT4 to the plasma membrane, organism-specific biosystem (from REACTOME)
Translocation of GLUT4 to the plasma membrane, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Vesicle-mediated transport, organism-specific biosystem (from REACTOME)
Vesicle-mediated transport, organism-specific biosystemcomputationally inferred pathway (not manually curated)

General gene information

Go to the top of the page Help

Markers

fb18b04.y1 (e-PCR)
- UniSTS:190232

AI496692 (e-PCR)
- UniSTS:206414

fe38c12.x1 (e-PCR)
- UniSTS:204374

fb34h10.x1 (e-PCR)
- UniSTS:203139

fc05a01.x1 (e-PCR)
- UniSTS:203699

fi22e10.x1 (e-PCR)
- UniSTS:204510

Homology

Homologs of the ywhae1 gene: The ywhae1 gene is conserved in chimpanzee, S.pombe, M.oryzae, A.thaliana, and rice.
Orthologs from Annotation Pipeline: 232 organisms have orthologs with human gene ywhae1
Orthologs

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
monooxygenase activity	IEA Inferred from Electronic Annotation more info
oxidoreductase activity	IEA Inferred from Electronic Annotation more info
protein domain specific binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
oxidation-reduction process	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: 14-3-3 protein epsilon

Names: 14-3-3 epsilon

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_212605.2 → NP_997770.1 14-3-3 protein epsilon

See identical proteins and their annotated locations for NP_997770.1

Status: VALIDATED

Source sequence(s)

BC160627, CR524483

UniProtKB/TrEMBL

Q7ZW20

Related

ENSDARP00000032575.5, ENSDART00000032306.7

Conserved Domains (1) summary

cd10020
Location:4 → 233

14-3-3_epsilon; 14-3-3 epsilon, an isoform of 14-3-3 protein

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007126.7 Reference GRCz11 Primary Assembly

Range

24746440..24755108

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021481333.1 → XP_021337008.1 14-3-3 protein epsilon isoform X1

Conserved Domains (1) summary

cd10020
Location:4 → 233

14-3-3_epsilon; 14-3-3 epsilon, an isoform of 14-3-3 protein