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rchy1 ring finger and CHY zinc finger domain containing 1 [ Danio rerio (zebrafish) ]

Gene ID: 321875, updated on 9-Sep-2025
Official Symbol
rchy1provided by ZNC
Official Full Name
ring finger and CHY zinc finger domain containing 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040801-73
See related
Ensembl:ENSDARG00000016710 AllianceGenome:ZFIN:ZDB-GENE-040801-73
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
Zfp363; wu:fb37e07; zgc:101128
Summary
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be active in nucleus. Is expressed in several structures, including axial chorda mesoderm; cleithrum; lens; notochord; and solid lens vesicle. Orthologous to human RCHY1 (ring finger and CHY zinc finger domain containing 1). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs
human mouse all
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See rchy1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2025_04 current GRCz12tu (GCF_049306965.1) 5 NC_133180.1 (9847189..9861172)
RS_2024_08 previous assembly GRCz11 (GCF_000002035.6) 5 NC_007116.7 (9147495..9161478)

Chromosome 5 - NC_133180.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC141385751 Neighboring gene Pim proto-oncogene, serine/threonine kinase, related 122 Neighboring gene Pim proto-oncogene, serine/threonine kinase, related 123 Neighboring gene uncharacterized LOC141385750 Neighboring gene low-density lipoprotein receptor related-protein 13

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Related articles in PubMed

  1. Lrp13 is a novel vertebrate lipoprotein receptor that binds vitellogenins in teleost fishes. Reading BJ, et al. J Lipid Res, 2014 Nov. PMID 25217480, Free PMC Article
  2. SPOUT1 variants associated with autosomal-recessive developmental and epileptic encephalopathy. Liu W, et al. Acta Epileptol, 2024 Dec 15. PMID 40217412, Free PMC Article
  3. Molecular Analysis of the HOXA2-Dependent Degradation of RCHY1. Bridoux L, et al. PLoS One, 2015. PMID 26496426, Free PMC Article
  4. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nuclear speck IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
Preferred Names
RING finger and CHY zinc finger domain-containing protein 1
NP_997765.2

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212600.2 → NP_997765.2  RING finger and CHY zinc finger domain-containing protein 1

    Status: VALIDATED

    Source sequence(s)
    JBMGRA010000005
    UniProtKB/TrEMBL
    A0A8M1PH56, Q90ZZ0
    Related
    ENSDARP00000013599.6, ENSDART00000003273.7

RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

  1. NC_133180.1 Reference GRCz12tu Primary Assembly

    Range
    9847189..9861172
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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