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cac cacophony [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32158, updated on 5-Mar-2017
Official Symbol
cacprovided by FlyBase
Official Full Name
cacophonyprovided by FlyBase
Primary source
FLYBASE:FBgn0263111
Locus tag
Dmel_CG43368
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
13; alpha1A; Ca-alpha1A; Cac; CAC; cac1; Cac1; Ca[[V]]2.1; CG1522; CG15928; CG43368; dCac1; Dmca1A; Dmcalpha1A; Dmel\CG43368; EE171; H18; H47; l(1)11Aa; l(1)13; l(1)L13; L13; ldg; nbA; nonB; opm18; opm47; P18
Old locus tag
Dmel_CG1522; Dmel_CG15928
Location:
10F8-11A1; 1-36.7 cM
Exon count:
40
Annotation release Status Assembly Chr Location
Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (11931280..11985087, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (11825313..11879120, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene CG2471 gene product from transcript CG2471-RC Neighboring gene CG10362 gene product from transcript CG10362-RA Neighboring gene gastrulation-defective Neighboring gene twisted gastrulation

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
high voltage-gated calcium channel activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
low voltage-gated calcium channel activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
voltage-gated calcium channel activity IDA
Inferred from Direct Assay
more info
PubMed 
voltage-gated calcium channel activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
voltage-gated calcium channel activity NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
adult locomotory behavior IGI
Inferred from Genetic Interaction
more info
PubMed 
adult locomotory behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
autophagosome maturation IMP
Inferred from Mutant Phenotype
more info
PubMed 
autophagy IMP
Inferred from Mutant Phenotype
more info
PubMed 
calcium ion transmembrane transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
calcium ion transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
calcium ion transport NAS
Non-traceable Author Statement
more info
PubMed 
calcium-mediated signaling IMP
Inferred from Mutant Phenotype
more info
PubMed 
chemical synaptic transmission IDA
Inferred from Direct Assay
more info
PubMed 
chemical synaptic transmission IMP
Inferred from Mutant Phenotype
more info
PubMed 
courtship behavior IMP
Inferred from Mutant Phenotype
more info
 
courtship behavior NAS
Non-traceable Author Statement
more info
PubMed 
detection of light stimulus involved in visual perception IMP
Inferred from Mutant Phenotype
more info
PubMed 
epithelial fluid transport IDA
Inferred from Direct Assay
more info
PubMed 
epithelial fluid transport IEP
Inferred from Expression Pattern
more info
PubMed 
exocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
male courtship behavior, veined wing generated song production IMP
Inferred from Mutant Phenotype
more info
PubMed 
male courtship behavior, veined wing generated song production NAS
Non-traceable Author Statement
more info
PubMed 
male courtship behavior, veined wing generated song production TAS
Traceable Author Statement
more info
PubMed 
neuron cellular homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
neuron remodeling IMP
Inferred from Mutant Phenotype
more info
PubMed 
neurotransmitter secretion IMP
Inferred from Mutant Phenotype
more info
PubMed 
NOT neurotransmitter secretion IMP
Inferred from Mutant Phenotype
more info
PubMed 
phototransduction NAS
Non-traceable Author Statement
more info
PubMed 
positive regulation of calcium ion transport into cytosol IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of synaptic growth at neuromuscular junction IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of heart rate IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of membrane potential in photoreceptor cell IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of neurotransmitter secretion IGI
Inferred from Genetic Interaction
more info
PubMed 
visual behavior NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
apical plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
basolateral plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
neuromuscular junction IMP
Inferred from Mutant Phenotype
more info
PubMed 
presynaptic active zone IDA
Inferred from Direct Assay
more info
PubMed 
voltage-gated calcium channel complex IGI
Inferred from Genetic Interaction
more info
PubMed 
voltage-gated calcium channel complex NAS
Non-traceable Author Statement
more info
PubMed 
Preferred Names
CG43368 gene product from transcript CG43368-RI
Names
CG43368-PA
CG43368-PB
CG43368-PC
CG43368-PD
CG43368-PE
CG43368-PF
CG43368-PG
CG43368-PH
CG43368-PI
CG43368-PJ
CG43368-PL
CG43368-PM
CG43368-PN
CG43368-PO
CG43368-PP
cac-PA
cac-PB
cac-PC
cac-PD
cac-PE
cac-PF
cac-PG
cac-PH
cac-PI
cac-PJ
cac-PL
cac-PM
cac-PN
cac-PO
cac-PP
cacaphony
cacophany
cacophony
calcium channel alpha1 subunit, type A
lamina-degeneration
lethal(1)11Aa
night blind A
nightblind
nightblind A
no-on-transient B

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    11931280..11985087 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001014733.5NP_001014733.1  cacophony, isoform I [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001014733.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q59E52
    Related
    FBpp0298316, FBtr0307315
    Conserved Domains (4) summary
    pfam00520
    Location:11121347
    Ion_trans; Ion transport protein
    pfam08763
    Location:14201494
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    pfam13136
    Location:15141667
    DUF3984; Protein of unknown function (DUF3984)
    pfam16905
    Location:13551418
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  2. NM_206696.5NP_996419.1  cacophony, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996419.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P91645
    Related
    FBpp0298318, FBtr0307317
    Conserved Domains (4) summary
    pfam00520
    Location:11121345
    Ion_trans; Ion transport protein
    pfam08763
    Location:14181492
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    pfam13136
    Location:15121665
    DUF3984; Protein of unknown function (DUF3984)
    pfam16905
    Location:13531416
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  3. NM_206693.5NP_996416.1  cacophony, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996416.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P91645
    Related
    FBpp0298321, FBtr0307320
    Conserved Domains (4) summary
    pfam00520
    Location:11121348
    Ion_trans; Ion transport protein
    pfam08763
    Location:14211495
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    pfam13136
    Location:15151668
    DUF3984; Protein of unknown function (DUF3984)
    pfam16905
    Location:13561419
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  4. NM_001258709.2NP_001245638.1  cacophony, isoform N [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245638.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9NGZ9
    Related
    FBpp0298326, FBtr0307325
    Conserved Domains (4) summary
    pfam00520
    Location:12181451
    Ion_trans; Ion transport protein
    pfam08763
    Location:15241598
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    pfam13136
    Location:16181771
    DUF3984; Protein of unknown function (DUF3984)
    pfam16905
    Location:14591522
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  5. NM_078578.5NP_511133.2  cacophony, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_511133.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P91645
    Related
    FBpp0298319, FBtr0307318
    Conserved Domains (4) summary
    pfam00520
    Location:11121345
    Ion_trans; Ion transport protein
    pfam08763
    Location:14181492
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    pfam13136
    Location:15121665
    DUF3984; Protein of unknown function (DUF3984)
    pfam16905
    Location:13531416
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  6. NM_001014734.4NP_001014734.1  cacophony, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001014734.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q59E53
    Related
    FBpp0298315, FBtr0307314
    Conserved Domains (4) summary
    pfam00520
    Location:11121346
    Ion_trans; Ion transport protein
    pfam08763
    Location:14191493
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    pfam13136
    Location:15131666
    DUF3984; Protein of unknown function (DUF3984)
    pfam16905
    Location:13541417
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  7. NM_001258708.2NP_001245637.1  cacophony, isoform M [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245637.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9NF25
    Related
    FBpp0298325, FBtr0307324
    Conserved Domains (3) summary
    pfam00520
    Location:11121347
    Ion_trans; Ion transport protein
    pfam08763
    Location:14201494
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    pfam16905
    Location:13551418
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  8. NM_001258707.2NP_001245636.1  cacophony, isoform L [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245636.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9NEE2
    Related
    FBpp0298324, FBtr0307323
    Conserved Domains (4) summary
    pfam00520
    Location:11121347
    Ion_trans; Ion transport protein
    pfam08763
    Location:14201494
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    pfam13136
    Location:15901743
    DUF3984; Protein of unknown function (DUF3984)
    pfam16905
    Location:13551418
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  9. NM_001258710.2NP_001245639.1  cacophony, isoform O [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245639.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P91645
    UniProtKB/TrEMBL
    M9NDV1
    Related
    FBpp0300833, FBtr0308609
    Conserved Domains (4) summary
    pfam00520
    Location:11121348
    Ion_trans; Ion transport protein
    pfam08763
    Location:14211495
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    pfam13136
    Location:15151668
    DUF3984; Protein of unknown function (DUF3984)
    pfam16905
    Location:13561419
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  10. NM_206695.4NP_996418.1  cacophony, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996418.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P91645
    Related
    FBpp0298320, FBtr0307319
    Conserved Domains (4) summary
    pfam00520
    Location:11121345
    Ion_trans; Ion transport protein
    pfam08763
    Location:14181492
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    pfam13136
    Location:15121665
    DUF3984; Protein of unknown function (DUF3984)
    pfam16905
    Location:13531416
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  11. NM_001014735.4NP_001014735.1  cacophony, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001014735.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q59E51
    Related
    FBpp0298314, FBtr0307313
    Conserved Domains (4) summary
    pfam00520
    Location:11121346
    Ion_trans; Ion transport protein
    pfam08763
    Location:14191493
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    pfam13136
    Location:15131666
    DUF3984; Protein of unknown function (DUF3984)
    pfam16905
    Location:13541417
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  12. NM_001014732.4NP_001014732.1  cacophony, isoform J [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001014732.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q59E50
    Related
    FBpp0298317, FBtr0307316
    Conserved Domains (4) summary
    pfam00520
    Location:11121347
    Ion_trans; Ion transport protein
    pfam08763
    Location:14201494
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    pfam13136
    Location:15141667
    DUF3984; Protein of unknown function (DUF3984)
    pfam16905
    Location:13551418
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  13. NM_206697.4NP_996420.1  cacophony, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996420.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P91645
    Related
    FBpp0298322, FBtr0307321
    Conserved Domains (4) summary
    pfam00520
    Location:11121345
    Ion_trans; Ion transport protein
    pfam08763
    Location:14181492
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    pfam13136
    Location:15121665
    DUF3984; Protein of unknown function (DUF3984)
    pfam16905
    Location:13531416
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  14. NM_206694.4NP_996417.1  cacophony, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996417.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P91645
    UniProtKB/TrEMBL
    M9NDV1
    Related
    FBpp0298323, FBtr0307322
    Conserved Domains (4) summary
    pfam00520
    Location:11121348
    Ion_trans; Ion transport protein
    pfam08763
    Location:14211495
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    pfam13136
    Location:15151668
    DUF3984; Protein of unknown function (DUF3984)
    pfam16905
    Location:13561419
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
  15. NM_001272548.1NP_001259477.1  cacophony, isoform P [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259477.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PHD4
    Related
    FBpp0304665, FBtr0332391
    Conserved Domains (4) summary
    pfam00520
    Location:11121346
    Ion_trans; Ion transport protein
    pfam08763
    Location:14191493
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    pfam13136
    Location:15331686
    DUF3984; Protein of unknown function (DUF3984)
    pfam16905
    Location:13541417
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
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