hnrnph1l heterogeneous nuclear ribonucleoprotein H1, like [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: hnrnph1lprovided by ZNC
Official Full Name: heterogeneous nuclear ribonucleoprotein H1, likeprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-275
See related: Ensembl:ENSDARG00000005551 AllianceGenome:ZFIN:ZDB-GENE-030131-275
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fb19a06; zgc:55399; zgc:85960; wu:fb19a06
Summary: Predicted to enable RNA binding activity. Predicted to be involved in regulation of RNA splicing. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleoplasm. Human ortholog(s) of this gene implicated in Sjogren's syndrome and syndromic X-linked intellectual disability. Orthologous to several human genes including HNRNPH1 (heterogeneous nuclear ribonucleoprotein H1) and HNRNPH2 (heterogeneous nuclear ribonucleoprotein H2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 21

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	21	NC_007132.7 (30169610..30181765, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	21	NC_007132.6 (30132915..30145035, complement)

Chromosome 21 - NC_007132.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in regulation of RNA splicing	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleoplasm	IBA Inferred from Biological aspect of Ancestor more info
part_of ribonucleoprotein complex	IBA Inferred from Biological aspect of Ancestor more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: heterogeneous nuclear ribonucleoprotein H1, like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_212589.2 → NP_997754.2 heterogeneous nuclear ribonucleoprotein H1, like

Status: VALIDATED

Source sequence(s)

AI723166, CT671502, EB830940, EH437757

UniProtKB/TrEMBL

A0A0R4IHE2, A0A8M1PHL5, F1QFJ8

Related

ENSDARP00000027385.7, ENSDART00000015636.9

Conserved Domains (4) summary

pfam08080
Location:237 → 255

zf-RNPHF; RNPHF zinc finger

COG0724
Location:58 → 168

RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

cd12734
Location:254 → 329

RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins

cl17169
Location:89 → 184

RRM_SF; RNA recognition motif (RRM) superfamily

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007132.7 Reference GRCz11 Primary Assembly

Range

30169610..30181765 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021468753.1 → XP_021324428.1 heterogeneous nuclear ribonucleoprotein H1, like isoform X1

UniProtKB/TrEMBL

A0A8M9PCG7

Conserved Domains (1) summary

cd12734
Location:57 → 132

RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins