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p24-1 p24-related-1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32140, updated on 5-Jan-2023

Summary

Official Symbol
p24-1provided by FlyBase
Official Full Name
p24-related-1provided by FlyBase
Primary source
FLYBASE:FBgn0030341
Locus tag
Dmel_CG1967
See related
AllianceGenome:FB:FBgn0030341
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-EST:Liang-1.45; CG1967; clone 1.45; Dmel\CG1967; p24; p24.1; p26/p24gamma4
Summary
Predicted to enable cargo receptor activity. Involved in Wnt protein secretion. Predicted to be integral component of membrane. Predicted to be active in several cellular components, including COPII-coated ER to Golgi transport vesicle; Golgi apparatus; and endoplasmic reticulum-Golgi intermediate compartment. Is expressed in several structures, including adult fat body; embryonic epidermis; gut section; proventriculus primordium; and reproductive system. Orthologous to human TMED7-TICAM2 (TMED7-TICAM2 readthrough) and TMED3 (transmembrane p24 trafficking protein 3). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See p24-1 in Genome Data Viewer
Location:
10F1-10F1; 1-37 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.46 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (11850909..11852530, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (11744942..11746563, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45619 Neighboring gene uncharacterized protein Neighboring gene ATP7 Neighboring gene Nardilysin

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the p24-1 gene: The p24-1 gene is conserved in human, chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, and frog.
  • Orthologs

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables cargo receptor activity ISM
Inferred from Sequence Model
more info
PubMed 
Process Evidence Code Pubs
involved_in Golgi organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in Golgi vesicle transport ISM
Inferred from Sequence Model
more info
PubMed 
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in COPII-coated ER to Golgi transport vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane ISM
Inferred from Sequence Model
more info
PubMed 

General protein information

Preferred Names
p24-related-1
Names
CG1967-PA
CG1967-PB
p24-1-PA
p24-1-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    11850909..11852530 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132526.4NP_572754.1  p24-related-1, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572754.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VYT6
    Related
    FBpp0073441, FBtr0073604
    Conserved Domains (1) summary
    pfam01105
    Location:21197
    EMP24_GP25L; emp24/gp25L/p24 family/GOLD
  2. NM_001272536.1NP_001259465.1  p24-related-1, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259465.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VYT6
    Related
    FBpp0306531, FBtr0334455
    Conserved Domains (1) summary
    pfam01105
    Location:21197
    EMP24_GP25L; emp24/gp25L/p24 family/GOLD