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id2b inhibitor of DNA binding 2b [ Danio rerio (zebrafish) ]

Gene ID: 321364, updated on 3-Oct-2019

Summary

Official Symbol
id2bprovided by ZNC
Official Full Name
inhibitor of DNA binding 2bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-15
See related
Ensembl:ENSDARG00000029544
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
id2l; zgc:73382; hm:zeh0152

Genomic context

See id2b in Genome Data Viewer
Location:
chromosome: 20
Exon count:
3
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (29784920..29787273, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (29882041..29884394, complement)
103 previous assembly Zv9 (GCF_000002035.4) 20 NC_007131.5 (29810829..29813181, complement)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene membrane bound O-acyltransferase domain containing 2b Neighboring gene kinase D-interacting substrate 220b Neighboring gene ring finger protein 144ab Neighboring gene SRY-box transcription factor 11b

Genomic regions, transcripts, and products

Pathways from BioSystems

  • Canonical wnt signaling, organism-specific biosystem (from WikiPathways)
    Canonical wnt signaling, organism-specific biosystem
    Canonical wnt signaling
  • TGF-beta signaling pathway, organism-specific biosystem (from KEGG)
    TGF-beta signaling pathway, organism-specific biosystemThe transforming growth factor-beta (TGF-beta) family members, which include TGF-betas, activins and bone morphogenetic proteins (BMPs), are structurally related secreted cytokines found in species r...
  • TGF-beta signaling pathway, conserved biosystem (from KEGG)
    TGF-beta signaling pathway, conserved biosystemThe transforming growth factor-beta (TGF-beta) family members, which include TGF-betas, activins and bone morphogenetic proteins (BMPs), are structurally related secreted cytokines found in species r...

General gene information

Markers

Clone Names

  • MGC113955

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II transcription factor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 
transcription factor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
circadian rhythm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of neuron differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
neuron differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
colocalizes_with cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, b; inhibitor of DNA binding 2b
Names
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, like

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199541.1NP_955835.1  inhibitor of DNA binding 2b

    See identical proteins and their annotated locations for NP_955835.1

    Status: PROVISIONAL

    Source sequence(s)
    BC059690
    UniProtKB/TrEMBL
    Q6PBJ0
    Related
    ENSDARP00000048758.3, ENSDART00000048759.4
    Conserved Domains (1) summary
    cd00083
    Location:3677
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    29784920..29787273 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005160630.2XP_005160687.1  inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, b isoform X1

    See identical proteins and their annotated locations for XP_005160687.1

    UniProtKB/TrEMBL
    Q6PBJ0
    Related
    ENSDARP00000108958.2, ENSDART00000125348.3
    Conserved Domains (1) summary
    cd00083
    Location:3677
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
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