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ap2m1a adaptor related protein complex 2 subunit mu 1a [ Danio rerio (zebrafish) ]

Gene ID: 321051, updated on 3-Oct-2019

Summary

Official Symbol
ap2m1aprovided by ZNC
Official Full Name
adaptor related protein complex 2 subunit mu 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-9784
See related
Ensembl:ENSDARG00000002790
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
cb34; Ap2m1; dpy-23; sb:cb34; zgc:55711; zgc:85653; wu:fa97a10

Genomic context

See ap2m1a in Genome Data Viewer
Location:
chromosome: 2
Exon count:
13
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (9789820..9818673, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (9992000..10020853, complement)
103 previous assembly Zv9 (GCF_000002035.4) 2 NC_007113.5 (9578717..9607572, complement)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108179500 Neighboring gene phosphate cytidylyltransferase 1, choline, alpha a Neighboring gene annexin A13, like Neighboring gene si:ch211-252f13.5

Genomic regions, transcripts, and products

Pathways from BioSystems

General gene information

Markers

Homology

  • Homologs of the ap2m1a gene: The ap2m1a gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, fruit fly, mosquito, C.elegans, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.
  • Orthologs

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
lipid binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
Wnt signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
endocytosis IEA
Inferred from Electronic Annotation
more info
 
intracellular protein transport IEA
Inferred from Electronic Annotation
more info
 
protein transport IEA
Inferred from Electronic Annotation
more info
 
vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
clathrin adaptor complex IEA
Inferred from Electronic Annotation
more info
 
clathrin-coated pit IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
AP-2 complex subunit mu-A
Names
AP-2 complex subunit mu-1-A
AP-2 mu-2 chain A
AP-2 mu-A chain
adaptor protein complex AP-2, mu1
adaptor-related protein complex 2, mu 1 subunit, a
clathrin assembly protein complex 2 medium chain A
clathrin assembly protein complex 2 mu-A medium chain
clathrin coat assembly protein AP50-A
clathrin coat-associated protein AP50-A
mu2-adaptin-A
plasma membrane adaptor AP-2 50 kDa protein A

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001291355.1NP_001278284.1  AP-2 complex subunit mu-A isoform 1

    See identical proteins and their annotated locations for NP_001278284.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1).
    Source sequence(s)
    BX470264, EB766597, EH432280, EH456153
    UniProtKB/TrEMBL
    A0A0R4IL09
    Related
    ENSDARP00000106819.2, ENSDART00000124051.3
    Conserved Domains (1) summary
    cd09251
    Location:168440
    AP-2_Mu2_Cterm; C-terminal domain of medium Mu2 subunit in ubiquitously expressed clathrin-associated adaptor protein (AP) complex AP-2
  2. NM_212577.2NP_997742.1  AP-2 complex subunit mu-A isoform 2

    See identical proteins and their annotated locations for NP_997742.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the coding region compared to variant 1. The resulting protein (isoform 2) is shorter but has the same N- and C-termini compared to isoform 1.
    Source sequence(s)
    BX470264, EB766597, EH432280, EH494715
    UniProtKB/Swiss-Prot
    Q6NWK2
    Related
    ENSDARP00000046586.5, ENSDART00000046587.7
    Conserved Domains (1) summary
    cd09251
    Location:168435
    AP-2_Mu2_Cterm; C-terminal domain of medium Mu2 subunit in ubiquitously expressed clathrin-associated adaptor protein (AP) complex AP-2

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    9789820..9818673 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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