Format

Send to:

Choose Destination

Cdh18 cadherin 18 [ Mus musculus (house mouse) ]

Gene ID: 320865, updated on 9-Sep-2018

Summary

Official Symbol
Cdh18provided by MGI
Official Full Name
cadherin 18provided by MGI
Primary source
MGI:MGI:1344366
See related
Ensembl:ENSMUSG00000040420 Vega:OTTMUSG00000036412
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Cdh14l; B230220E17Rik; Tg(GFAP-APOE_i4)1Hol
Expression
Biased expression in cerebellum adult (RPKM 8.0), cortex adult (RPKM 2.6) and 5 other tissues See more
Orthologs

Genomic context

See Cdh18 in Genome Data Viewer
Location:
15; 15 A2
Exon count:
15
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 15 NC_000081.6 (22548897..23474432)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (22966218..23404173)

Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene cadherin 12 Neighboring gene 60S ribosomal protein L37 pseudogene Neighboring gene predicted gene, 41278 Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like 2, pseudogene 2 Neighboring gene 60S ribosomal protein L5-like Neighboring gene predicted gene 6533 Neighboring gene BRCA1 associated RING domain 1 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
cadherin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoskeletal protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein homodimerization activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
adherens junction organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell-cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell-cell adhesion mediated by cadherin IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell-cell junction assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
homophilic cell adhesion via plasma membrane adhesion molecules IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
catenin complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell surface IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell-cell adherens junction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
cadherin-18
Names
GFAP-apoE4 line1
Tg(GFAP-APOE*4)1Hol
Tg(GFAP-APOE4)1Hol

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081299.1NP_001074768.1  cadherin-18 precursor

    See identical proteins and their annotated locations for NP_001074768.1

    Status: VALIDATED

    Source sequence(s)
    AC121357, AC134595, AC134864, AC157478
    Consensus CDS
    CCDS49585.1
    UniProtKB/TrEMBL
    E9Q9Q6
    Related
    ENSMUSP00000130851.1, OTTMUSP00000051736, ENSMUST00000164787.7, OTTMUST00000093314
    Conserved Domains (3) summary
    cd11304
    Location:387484
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00112
    Location:79157
    CA; Cadherin repeats
    pfam01049
    Location:644782
    Cadherin_C; Cadherin cytoplasmic region

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000081.6 Reference GRCm38.p4 C57BL/6J

    Range
    22548897..23474432
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006520095.3XP_006520158.1  cadherin-18 isoform X1

    See identical proteins and their annotated locations for XP_006520158.1

    UniProtKB/TrEMBL
    E9Q9Q6
    Conserved Domains (3) summary
    cd11304
    Location:387484
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00112
    Location:79157
    CA; Cadherin repeats
    pfam01049
    Location:644782
    Cadherin_C; Cadherin cytoplasmic region
  2. XM_006520097.3XP_006520160.1  cadherin-18 isoform X2

    Related
    ENSMUSP00000153905.1, ENSMUST00000226693.1
    Conserved Domains (2) summary
    cd11304
    Location:387484
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00112
    Location:79157
    CA; Cadherin repeats
  3. XM_006520098.3XP_006520161.1  cadherin-18 isoform X3

    UniProtKB/TrEMBL
    E9Q941
    Related
    ENSMUSP00000128643.1, OTTMUSP00000051737, ENSMUST00000165614.8, OTTMUST00000093315
    Conserved Domains (2) summary
    cd11304
    Location:387484
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00112
    Location:79157
    CA; Cadherin repeats
  4. XM_011245360.2XP_011243662.1  cadherin-18 isoform X1

    See identical proteins and their annotated locations for XP_011243662.1

    UniProtKB/TrEMBL
    E9Q9Q6
    Conserved Domains (3) summary
    cd11304
    Location:387484
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00112
    Location:79157
    CA; Cadherin repeats
    pfam01049
    Location:644782
    Cadherin_C; Cadherin cytoplasmic region
  5. XM_006520094.3XP_006520157.1  cadherin-18 isoform X1

    See identical proteins and their annotated locations for XP_006520157.1

    UniProtKB/TrEMBL
    E9Q9Q6
    Conserved Domains (3) summary
    cd11304
    Location:387484
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00112
    Location:79157
    CA; Cadherin repeats
    pfam01049
    Location:644782
    Cadherin_C; Cadherin cytoplasmic region
  6. XM_006520096.3XP_006520159.1  cadherin-18 isoform X1

    See identical proteins and their annotated locations for XP_006520159.1

    UniProtKB/TrEMBL
    E9Q9Q6
    Conserved Domains (3) summary
    cd11304
    Location:387484
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00112
    Location:79157
    CA; Cadherin repeats
    pfam01049
    Location:644782
    Cadherin_C; Cadherin cytoplasmic region
Support Center