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Negr1 neuronal growth regulator 1 [ Mus musculus (house mouse) ]

Gene ID: 320840, updated on 12-Nov-2019

Summary

Official Symbol
Negr1provided by MGI
Official Full Name
neuronal growth regulator 1provided by MGI
Primary source
MGI:MGI:2444846
See related
Ensembl:ENSMUSG00000040037
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ntra; KILON; 5330422G01Rik
Expression
Biased expression in CNS E18 (RPKM 8.0), frontal lobe adult (RPKM 7.4) and 9 other tissues See more
Orthologs

Genomic context

See Negr1 in Genome Data Viewer
Location:
3; 3 H4
Exon count:
11
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (156561790..157316464)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (156224758..156979411)

Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 33311 Neighboring gene RIKEN cDNA 4930570G19 gene Neighboring gene predicted gene, 24373 Neighboring gene predicted gene, 23725 Neighboring gene predicted gene, 22458 Neighboring gene predicted gene, 23379

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Clone Names

  • mKIAA3001

Gene Ontology Provided by MGI

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
cell adhesion IEA
Inferred from Electronic Annotation
more info
 
cell-cell adhesion IDA
Inferred from Direct Assay
more info
PubMed 
feeding behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
locomotory behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of neuron projection development IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
anchored component of membrane IEA
Inferred from Electronic Annotation
more info
 
dendrite ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
neuronal growth regulator 1
Names
kindred of IgLON
neurotractin

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039094.3NP_001034183.1  neuronal growth regulator 1 isoform a precursor

    See identical proteins and their annotated locations for NP_001034183.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AK147253, CA884108
    Consensus CDS
    CCDS17930.1
    UniProtKB/Swiss-Prot
    Q80Z24
    Related
    ENSMUSP00000073664.4, ENSMUST00000074015.10
    Conserved Domains (4) summary
    cd00096
    Location:237303
    Ig; Immunoglobulin domain
    smart00408
    Location:146204
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:225306
    IG_like; Immunoglobulin like
    cl11960
    Location:38129
    Ig; Immunoglobulin domain
  2. NM_177274.4NP_796248.1  neuronal growth regulator 1 isoform b precursor

    See identical proteins and their annotated locations for NP_796248.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an alternate 3' terminal exon which results in a frameshift compared to variant 1. The encoded protein (isoform b) is shorter and has a distinct C-terminus compared to isoform a.
    Source sequence(s)
    AK035218, AK147253
    Consensus CDS
    CCDS17931.1
    UniProtKB/Swiss-Prot
    Q80Z24
    UniProtKB/TrEMBL
    A0A4W9
    Related
    ENSMUSP00000041132.5, ENSMUST00000041425.11
    Conserved Domains (4) summary
    cd00096
    Location:237303
    Ig; Immunoglobulin domain
    smart00408
    Location:146204
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:225306
    IG_like; Immunoglobulin like
    cl11960
    Location:38129
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000069.6 Reference GRCm38.p6 C57BL/6J

    Range
    156561790..157316464
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006501576.3XP_006501639.1  neuronal growth regulator 1 isoform X1

    Conserved Domains (4) summary
    cd00096
    Location:237303
    Ig; Immunoglobulin domain
    smart00408
    Location:146204
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:225306
    IG_like; Immunoglobulin like
    cl11960
    Location:38129
    Ig; Immunoglobulin domain
  2. XM_006501578.3XP_006501641.1  neuronal growth regulator 1 isoform X3

    Conserved Domains (4) summary
    cd00096
    Location:237303
    Ig; Immunoglobulin domain
    smart00408
    Location:146204
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:225306
    IG_like; Immunoglobulin like
    cl11960
    Location:38129
    Ig; Immunoglobulin domain
  3. XM_006501577.2XP_006501640.1  neuronal growth regulator 1 isoform X2

    See identical proteins and their annotated locations for XP_006501640.1

    UniProtKB/TrEMBL
    D3Z4T6
    Related
    ENSMUSP00000101680.1, ENSMUST00000106065.1
    Conserved Domains (4) summary
    cd00096
    Location:237303
    Ig; Immunoglobulin domain
    smart00408
    Location:146204
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:225306
    IG_like; Immunoglobulin like
    cl11960
    Location:38129
    Ig; Immunoglobulin domain
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