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Sirpb1a signal-regulatory protein beta 1A [ Mus musculus (house mouse) ]

Gene ID: 320832, updated on 23-May-2018

Summary

Official Symbol
Sirpb1aprovided by MGI
Official Full Name
signal-regulatory protein beta 1Aprovided by MGI
Primary source
MGI:MGI:2444824
See related
Ensembl:ENSMUSG00000095788 Vega:OTTMUSG00000052297
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Sirpb; Sirpb1; SIRP-beta; 9930027N05Rik
Expression
Biased expression in spleen adult (RPKM 1.3), testis adult (RPKM 1.1) and 9 other tissues See more

Genomic context

See Sirpb1a in Genome Data Viewer
Location:
3; 3 A1
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (15371661..15426522, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (15371827..15426427, complement)

Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 33819 Neighboring gene predicted gene 9733 Neighboring gene signal-regulatory protein beta 1B Neighboring gene zinc finger protein 947 pseudogene Neighboring gene signal-regulatory protein beta 1-like

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from BioSystems

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
intracellular signal transduction IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of phagocytosis IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
signal-regulatory protein beta 1
Names
SIRP beta 1 cell surface protein
SIRP-beta B

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002898.1NP_001002898.1  signal-regulatory protein beta 1

    See identical proteins and their annotated locations for NP_001002898.1

    Status: PROVISIONAL

    Source sequence(s)
    AB112022
    Consensus CDS
    CCDS17252.1
    UniProtKB/TrEMBL
    Q6F5F2
    Related
    ENSMUSP00000141504.1, OTTMUSP00000070244, ENSMUST00000192700.2, OTTMUST00000131320
    Conserved Domains (4) summary
    cd00098
    Location:247341
    IgC; Immunoglobulin Constant domain
    smart00410
    Location:42119
    IG_like; Immunoglobulin like
    pfam07686
    Location:45143
    V-set; Immunoglobulin V-set domain
    cl11960
    Location:142252
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

    Range
    15371661..15426522 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017319615.1XP_017175104.1  signal-regulatory protein beta 1 isoform X1

  2. XM_006530073.1XP_006530136.1  signal-regulatory protein beta 1 isoform X2

    Conserved Domains (4) summary
    cd00098
    Location:180274
    IgC; Immunoglobulin Constant domain
    smart00410
    Location:2852
    IG_like; Immunoglobulin like
    pfam07686
    Location:3076
    V-set; Immunoglobulin V-set domain
    cl11960
    Location:75185
    Ig; Immunoglobulin domain
  3. XM_006530074.1XP_006530137.1  signal-regulatory protein beta 1 isoform X3

    See identical proteins and their annotated locations for XP_006530137.1

    Conserved Domains (2) summary
    cd00098
    Location:98192
    IgC; Immunoglobulin Constant domain
    cl11960
    Location:1103
    Ig; Immunoglobulin domain
  4. XM_006530076.3XP_006530139.1  signal-regulatory protein beta 1 isoform X3

    See identical proteins and their annotated locations for XP_006530139.1

    Conserved Domains (2) summary
    cd00098
    Location:98192
    IgC; Immunoglobulin Constant domain
    cl11960
    Location:1103
    Ig; Immunoglobulin domain
  5. XM_006530075.3XP_006530138.1  signal-regulatory protein beta 1 isoform X3

    See identical proteins and their annotated locations for XP_006530138.1

    Conserved Domains (2) summary
    cd00098
    Location:98192
    IgC; Immunoglobulin Constant domain
    cl11960
    Location:1103
    Ig; Immunoglobulin domain

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_178792.3: Suppressed sequence

    Description
    NM_178792.3: This RefSeq was temporarily suppressed because the protein is not supported by available homology data.
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