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Fastkd1 FAST kinase domains 1 [ Mus musculus (house mouse) ]

Gene ID: 320720, updated on 5-Mar-2024

Summary

Official Symbol
Fastkd1provided by MGI
Official Full Name
FAST kinase domains 1provided by MGI
Primary source
MGI:MGI:2444596
See related
Ensembl:ENSMUSG00000027086 AllianceGenome:MGI:2444596
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA1800; 5330408N05Rik
Summary
Predicted to enable RNA binding activity. Predicted to be involved in mitochondrial RNA processing and regulation of mitochondrial mRNA stability. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial matrix and ribonucleoprotein granule. Is expressed in central nervous system; retina inner nuclear layer; and retina outer nuclear layer. Orthologous to human FASTKD1 (FAST kinase domains 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E18 (RPKM 4.3), CNS E11.5 (RPKM 3.6) and 27 other tissues See more
Orthologs
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Genomic context

See Fastkd1 in Genome Data Viewer
Location:
2 C2; 2 40.93 cM
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (69517159..69543875, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (69686820..69712606, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene Bardet-Biedl syndrome 5 Neighboring gene kelch-like 41 Neighboring gene STARR-seq mESC enhancer starr_04743 Neighboring gene STARR-positive B cell enhancer ABC_E10110 Neighboring gene peptidyl-prolyl isomerase G (cyclophilin G) Neighboring gene STARR-positive B cell enhancer mm9_chr2:69582878-69583179 Neighboring gene 60S ribosomal protein L13-like Neighboring gene cilia and flagella associated protein 210 Neighboring gene STARR-seq mESC enhancer starr_04744

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • KIAA1800

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in mitochondrial RNA metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in mitochondrial RNA processing IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of mitochondrial mRNA stability IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of mitochondrial mRNA stability ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in mitochondrial matrix IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
is_active_in ribonucleoprotein granule IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
FAST kinase domain-containing protein 1, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177244.3NP_796218.2  FAST kinase domain-containing protein 1, mitochondrial

    See identical proteins and their annotated locations for NP_796218.2

    Status: PROVISIONAL

    Source sequence(s)
    BC075689
    Consensus CDS
    CCDS16096.1
    UniProtKB/Swiss-Prot
    A2AR00, B0R0D3, Q5DTU7, Q6DI86, Q6IS39, Q8BSV8, Q8C429, Q8R1N6
    Related
    ENSMUSP00000072896.7, ENSMUST00000073152.13
    Conserved Domains (3) summary
    smart00952
    Location:763821
    RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
    pfam06743
    Location:560628
    FAST_1; FAST kinase-like protein, subdomain 1
    pfam08368
    Location:648729
    FAST_2; FAST kinase-like protein, subdomain 2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    69517159..69543875 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036162311.1XP_036018204.1  FAST kinase domain-containing protein 1, mitochondrial isoform X1

    Conserved Domains (3) summary
    smart00952
    Location:635693
    RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
    pfam06743
    Location:432500
    FAST_1; FAST kinase-like protein, subdomain 1
    pfam08368
    Location:519601
    FAST_2; FAST kinase-like protein, subdomain 2

RNA

  1. XR_004940626.1 RNA Sequence