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Slc26a9 solute carrier family 26, member 9 [ Mus musculus (house mouse) ]

Gene ID: 320718, updated on 27-Nov-2024

Summary

Official Symbol
Slc26a9provided by MGI
Official Full Name
solute carrier family 26, member 9provided by MGI
Primary source
MGI:MGI:2444594
See related
Ensembl:ENSMUSG00000042268 AllianceGenome:MGI:2444594
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
E030002L01Rik
Summary
Enables chloride channel activity; chloride:bicarbonate antiporter activity; and identical protein binding activity. Involved in monoatomic anion transport. Acts upstream of or within bicarbonate transport; chloride transport; and regulation of pH. Located in apical plasma membrane. Is expressed in several structures, including adrenal gland; nervous system; respiratory system; and sensory organ. Orthologous to human SLC26A9 (solute carrier family 26 member 9). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in stomach adult (RPKM 21.9) and lung adult (RPKM 13.8) See more
Orthologs
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Genomic context

See Slc26a9 in Genome Data Viewer
Location:
1 E4; 1 57.18 cM
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (131671760..131699242)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (131744022..131771504)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene RAB7B, member RAS oncogene family Neighboring gene predicted gene, 30104 Neighboring gene STARR-seq mESC enhancer starr_02224 Neighboring gene peptidase M20 domain containing 1 Neighboring gene STARR-seq mESC enhancer starr_02225 Neighboring gene STARR-positive B cell enhancer ABC_E8960 Neighboring gene solute carrier family 41, member 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATPase binding ISO
Inferred from Sequence Orthology
more info
 
enables bicarbonate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables bicarbonate transmembrane transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
enables chloride channel activity IDA
Inferred from Direct Assay
more info
PubMed 
enables chloride channel activity ISO
Inferred from Sequence Orthology
more info
 
enables chloride transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables chloride:bicarbonate antiporter activity IDA
Inferred from Direct Assay
more info
PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables oxalate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables solute:inorganic anion antiporter activity ISO
Inferred from Sequence Orthology
more info
 
enables sulfate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within bicarbonate transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in chloride transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in chloride transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in chloride transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within chloride transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in chloride transport ISO
Inferred from Sequence Orthology
more info
 
involved_in monoatomic anion transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in monoatomic anion transport ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within regulation of pH IDA
Inferred from Direct Assay
more info
PubMed 
involved_in sulfate transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in Golgi membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in Golgi membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in apical plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in apical plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in cell surface ISO
Inferred from Sequence Orthology
more info
 
is_active_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in endoplasmic reticulum membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in endosome membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in endosome membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
solute carrier family 26 member 9
Names
SLC26A9 anion transporter/exchanger
anion transporter/exchanger protein 9
anion transporter/exchanger-9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177243.4NP_796217.2  solute carrier family 26 member 9

    See identical proteins and their annotated locations for NP_796217.2

    Status: VALIDATED

    Source sequence(s)
    AK078966, AK086815
    Consensus CDS
    CCDS15273.1
    UniProtKB/Swiss-Prot
    Q8BU91, Q8BVC3
    UniProtKB/TrEMBL
    A0A0R4J0F7
    Related
    ENSMUSP00000036916.4, ENSMUST00000049027.10
    Conserved Domains (1) summary
    TIGR00815
    Location:57733
    sulP; high affinity sulphate transporter 1

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    131671760..131699242
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006529700.2XP_006529763.1  solute carrier family 26 member 9 isoform X1

    See identical proteins and their annotated locations for XP_006529763.1

    UniProtKB/Swiss-Prot
    Q8BU91, Q8BVC3
    UniProtKB/TrEMBL
    A0A0R4J0F7
    Conserved Domains (1) summary
    TIGR00815
    Location:57733
    sulP; high affinity sulphate transporter 1
  2. XM_030254980.1XP_030110840.1  solute carrier family 26 member 9 isoform X2

    Conserved Domains (1) summary
    TIGR00815
    Location:7457
    sulP; high affinity sulphate transporter 1
  3. XM_006529701.1XP_006529764.1  solute carrier family 26 member 9 isoform X2

    Conserved Domains (1) summary
    TIGR00815
    Location:7457
    sulP; high affinity sulphate transporter 1

RNA

  1. XR_387176.2 RNA Sequence