U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Samd12 sterile alpha motif domain containing 12 [ Mus musculus (house mouse) ]

Gene ID: 320679, updated on 11-Apr-2024

Summary

Official Symbol
Samd12provided by MGI
Official Full Name
sterile alpha motif domain containing 12provided by MGI
Primary source
MGI:MGI:2444518
See related
Ensembl:ENSMUSG00000058656 AllianceGenome:MGI:2444518
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
A830094I09Rik
Summary
Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be active in cytoplasmic side of plasma membrane. Human ortholog(s) of this gene implicated in familial adult myoclonic epilepsy 1. Orthologous to human SAMD12 (sterile alpha motif domain containing 12). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in frontal lobe adult (RPKM 2.2), CNS E18 (RPKM 2.1) and 13 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Samd12 in Genome Data Viewer
Location:
15 C- D1; 15 21.1 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (53262514..53765926, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (53399113..53902535, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_38673 Neighboring gene STARR-seq mESC enhancer starr_38674 Neighboring gene exostosin glycosyltransferase 1 Neighboring gene STARR-seq mESC enhancer starr_38679 Neighboring gene STARR-seq mESC enhancer starr_38681 Neighboring gene STARR-positive B cell enhancer mm9_chr15:53231912-53232213 Neighboring gene STARR-seq mESC enhancer starr_38683 Neighboring gene STARR-positive B cell enhancer mm9_chr15:53246502-53246803 Neighboring gene predicted gene, 27926 Neighboring gene STARR-seq mESC enhancer starr_38684 Neighboring gene predicted gene, 23200 Neighboring gene microRNA 28c Neighboring gene STARR-seq mESC enhancer starr_38685 Neighboring gene predicted gene 7489 Neighboring gene STARR-seq mESC enhancer starr_38686 Neighboring gene tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) Neighboring gene ribosomal protein L19 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasmic side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
sterile alpha motif domain-containing protein 12
Names
SAM domain-containing protein 12

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177225.4NP_796199.1  sterile alpha motif domain-containing protein 12

    See identical proteins and their annotated locations for NP_796199.1

    Status: PROVISIONAL

    Source sequence(s)
    AC122341, AC123675, AC160638
    Consensus CDS
    CCDS37072.1
    UniProtKB/Swiss-Prot
    Q0VE29
    UniProtKB/TrEMBL
    B7ZN34
    Related
    ENSMUSP00000077741.7, ENSMUST00000078673.14
    Conserved Domains (2) summary
    cd09510
    Location:72146
    SAM_aveugle-like; SAM domain of aveugle-like subfamily
    smart00454
    Location:74141
    SAM; Sterile alpha motif

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    53262514..53765926 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011245660.4XP_011243962.1  sterile alpha motif domain-containing protein 12 isoform X2

    UniProtKB/TrEMBL
    B7ZN34
    Conserved Domains (1) summary
    cd09510
    Location:72146
    SAM_aveugle-like; SAM domain of aveugle-like subfamily
  2. XM_006521080.5XP_006521143.1  sterile alpha motif domain-containing protein 12 isoform X1

    Conserved Domains (1) summary
    cd09510
    Location:72146
    SAM_aveugle-like; SAM domain of aveugle-like subfamily
  3. XM_006521085.5XP_006521148.1  sterile alpha motif domain-containing protein 12 isoform X7

    UniProtKB/TrEMBL
    B7ZN34
    Conserved Domains (1) summary
    cl15755
    Location:72136
    SAM_superfamily; SAM (Sterile alpha motif )
  4. XM_006521081.5XP_006521144.1  sterile alpha motif domain-containing protein 12 isoform X3

    UniProtKB/TrEMBL
    B7ZN34
    Conserved Domains (1) summary
    cl15755
    Location:72136
    SAM_superfamily; SAM (Sterile alpha motif )
  5. XM_006521084.5XP_006521147.1  sterile alpha motif domain-containing protein 12 isoform X6

    UniProtKB/TrEMBL
    B7ZN34
    Conserved Domains (1) summary
    cd09510
    Location:72146
    SAM_aveugle-like; SAM domain of aveugle-like subfamily
  6. XM_036159467.1XP_036015360.1  sterile alpha motif domain-containing protein 12 isoform X4

    UniProtKB/TrEMBL
    B7ZN34
    Conserved Domains (1) summary
    cd09510
    Location:72146
    SAM_aveugle-like; SAM domain of aveugle-like subfamily
  7. XM_006521083.5XP_006521146.1  sterile alpha motif domain-containing protein 12 isoform X5

    Conserved Domains (1) summary
    cl15755
    Location:7299
    SAM_superfamily; SAM (Sterile alpha motif )