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Pgap3 post-GPI attachment to proteins 3 [ Mus musculus (house mouse) ]

Gene ID: 320655, updated on 13-Oct-2022

Summary

Official Symbol
Pgap3provided by MGI
Official Full Name
post-GPI attachment to proteins 3provided by MGI
Primary source
MGI:MGI:2444461
See related
Ensembl:ENSMUSG00000038208 AllianceGenome:MGI:2444461
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CAB2; Perld1; D430035D22Rik
Summary
Predicted to enable hydrolase activity, acting on ester bonds. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and membrane. Predicted to be integral component of membrane. Predicted to be intrinsic component of endoplasmic reticulum membrane. Orthologous to human PGAP3 (post-GPI attachment to proteins phospholipase 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in colon adult (RPKM 24.1), duodenum adult (RPKM 23.9) and 28 other tissues See more
Orthologs
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Genomic context

See Pgap3 in Genome Data Viewer
Location:
11; 11 D
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (98279498..98292022, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (98388672..98401196, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene titin-cap Neighboring gene phenylethanolamine-N-methyltransferase Neighboring gene erb-b2 receptor tyrosine kinase 2 Neighboring gene migration and invasion enhancer 1 Neighboring gene growth factor receptor bound protein 7

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3)  1 citation
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables hydrolase activity, acting on ester bonds IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables hydrolase activity, acting on ester bonds ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in GPI anchor biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in GPI anchor biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in GPI anchor metabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
post-GPI attachment to proteins factor 3
Names
PER1-like domain-containing protein 1
per1-like domain containing 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033537.2NP_001028709.2  post-GPI attachment to proteins factor 3 precursor

    See identical proteins and their annotated locations for NP_001028709.2

    Status: VALIDATED

    Source sequence(s)
    AL591390
    Consensus CDS
    CCDS25348.1
    UniProtKB/Swiss-Prot
    A2A559, Q3TCA8
    Related
    ENSMUSP00000088337.6, ENSMUST00000090827.12
    Conserved Domains (1) summary
    pfam04080
    Location:54306
    Per1; Per1-like

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    98279498..98292022 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006533549.4XP_006533612.1  post-GPI attachment to proteins factor 3 isoform X1

    UniProtKB/Swiss-Prot
    A2A559
    Related
    ENSMUSP00000119668.2, ENSMUST00000128897.2
    Conserved Domains (1) summary
    pfam04080
    Location:54255
    Per1; Per1-like family
  2. XM_006533550.5XP_006533613.1  post-GPI attachment to proteins factor 3 isoform X2

    Conserved Domains (1) summary
    pfam04080
    Location:1234
    Per1; Per1-like family