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Dop1a DOP1 leucine zipper like protein A [ Mus musculus (house mouse) ]

Gene ID: 320615, updated on 26-Sep-2022

Summary

Official Symbol
Dop1aprovided by MGI
Official Full Name
DOP1 leucine zipper like protein Aprovided by MGI
Primary source
MGI:MGI:1289294
See related
Ensembl:ENSMUSG00000034973 AllianceGenome:MGI:1289294
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Dopey1; C130028L17; D9Ertd809e; B130005I07Rik
Summary
Predicted to be involved in Golgi to endosome transport. Predicted to act upstream of or within protein transport. Predicted to be located in Golgi-associated vesicle. Predicted to be active in endosome and trans-Golgi network. Predicted to colocalize with Golgi apparatus. Is expressed in cerebellum and spleen. Orthologous to human DOP1A (DOP1 leucine zipper like protein A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E18 (RPKM 6.0), CNS E14 (RPKM 5.1) and 27 other tissues See more
Orthologs
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Genomic context

See Dop1a in Genome Data Viewer
Location:
9 E3.1; 9 46.58 cM
Exon count:
41
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (86349194..86437859)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (86467141..86555806)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene VISTA enhancer mm1553 Neighboring gene ubiquitin-conjugating enzyme E2C binding protein Neighboring gene sorting nexin 4 pseudogene Neighboring gene phosphoglucomutase 3 Neighboring gene RWD domain containing 2A Neighboring gene malic enzyme 1, NADP(+)-dependent, cytosolic Neighboring gene RIKEN cDNA A330041J22 gene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA1117, MGC49390

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in Golgi to endosome transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
colocalizes_with Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
located_in Golgi-associated vesicle ISO
Inferred from Sequence Orthology
more info
 
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
protein dopey-1
Names
dopey family member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001408204.1NP_001395133.1  protein dopey-1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC157998
  2. NM_001408205.1NP_001395134.1  protein dopey-1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC157998
  3. NM_177208.4NP_796182.2  protein dopey-1 isoform 1

    See identical proteins and their annotated locations for NP_796182.2

    Status: VALIDATED

    Source sequence(s)
    AC157998
    Consensus CDS
    CCDS52876.1
    UniProtKB/TrEMBL
    H7BWZ9
    Related
    ENSMUSP00000034987.9, ENSMUST00000034987.15
    Conserved Domains (2) summary
    pfam04118
    Location:13297
    Dopey_N; Dopey, N-terminal
    cl04407
    Location:20882324
    Dopey_N; Dopey, N-terminal

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    86349194..86437859
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006511239.4XP_006511302.1  protein dopey-1 isoform X7

    Conserved Domains (2) summary
    pfam04118
    Location:13297
    Dopey_N; Dopey, N-terminal
    cl04407
    Location:20892325
    Dopey_N; Dopey, N-terminal
  2. XM_006511240.4XP_006511303.1  protein dopey-1 isoform X8

    See identical proteins and their annotated locations for XP_006511303.1

    UniProtKB/TrEMBL
    H7BWZ9
    Related
    ENSMUSP00000140740.2, ENSMUST00000190957.7
    Conserved Domains (2) summary
    pfam04118
    Location:13297
    Dopey_N; Dopey, N-terminal
    cl04407
    Location:20882324
    Dopey_N; Dopey, N-terminal
  3. XM_036155067.1XP_036010960.1  protein dopey-1 isoform X10

    Conserved Domains (2) summary
    pfam04118
    Location:13297
    Dopey_N; Dopey, N-terminal
    cl04407
    Location:20792315
    Dopey_N; Dopey, N-terminal
  4. XM_036155068.1XP_036010961.1  protein dopey-1 isoform X12

    Conserved Domains (2) summary
    pfam04118
    Location:13297
    Dopey_N; Dopey, N-terminal
    cl04407
    Location:20782314
    Dopey_N; Dopey, N-terminal
  5. XM_030244420.1XP_030100280.1  protein dopey-1 isoform X9

    Conserved Domains (2) summary
    pfam04118
    Location:13295
    Dopey_N; Dopey, N-terminal
    cl04407
    Location:20802316
    Dopey_N; Dopey, N-terminal
  6. XM_006511241.4XP_006511304.1  protein dopey-1 isoform X11

    Conserved Domains (2) summary
    pfam04118
    Location:13295
    Dopey_N; Dopey, N-terminal
    cl04407
    Location:20792315
    Dopey_N; Dopey, N-terminal
  7. XM_017313433.2XP_017168922.1  protein dopey-1 isoform X1

    Conserved Domains (2) summary
    pfam04118
    Location:13297
    Dopey_N; Dopey, N-terminal
    cl04407
    Location:20892325
    Dopey_N; Dopey, N-terminal
  8. XM_006511236.4XP_006511299.1  protein dopey-1 isoform X2

    Conserved Domains (2) summary
    pfam04118
    Location:13297
    Dopey_N; Dopey, N-terminal
    cl04407
    Location:20882324
    Dopey_N; Dopey, N-terminal
  9. XM_006511237.4XP_006511300.1  protein dopey-1 isoform X4

    Conserved Domains (2) summary
    pfam04118
    Location:13297
    Dopey_N; Dopey, N-terminal
    cl04407
    Location:20792315
    Dopey_N; Dopey, N-terminal
  10. XM_036155066.1XP_036010959.1  protein dopey-1 isoform X6

    Conserved Domains (2) summary
    pfam04118
    Location:13297
    Dopey_N; Dopey, N-terminal
    cl04407
    Location:20782314
    Dopey_N; Dopey, N-terminal
  11. XM_017313434.2XP_017168923.1  protein dopey-1 isoform X3

    Conserved Domains (2) summary
    pfam04118
    Location:13295
    Dopey_N; Dopey, N-terminal
    cl04407
    Location:20802316
    Dopey_N; Dopey, N-terminal
  12. XM_006511238.4XP_006511301.1  protein dopey-1 isoform X5

    Conserved Domains (2) summary
    pfam04118
    Location:13295
    Dopey_N; Dopey, N-terminal
    cl04407
    Location:20792315
    Dopey_N; Dopey, N-terminal
  13. XM_006511235.4XP_006511298.1  protein dopey-1 isoform X1

    Conserved Domains (2) summary
    pfam04118
    Location:13297
    Dopey_N; Dopey, N-terminal
    cl04407
    Location:20892325
    Dopey_N; Dopey, N-terminal
  14. XM_017313435.1XP_017168924.1  protein dopey-1 isoform X15

    Conserved Domains (1) summary
    cl04407
    Location:15261762
    Dopey_N; Dopey, N-terminal
  15. XM_011242758.3XP_011241060.1  protein dopey-1 isoform X13

    Conserved Domains (1) summary
    cl04407
    Location:15261762
    Dopey_N; Dopey, N-terminal
  16. XM_011242759.3XP_011241061.1  protein dopey-1 isoform X14

    Conserved Domains (1) summary
    cl04407
    Location:15251761
    Dopey_N; Dopey, N-terminal

RNA

  1. XR_004935458.1 RNA Sequence

  2. XR_379426.5 RNA Sequence

  3. XR_004935457.1 RNA Sequence