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Tmem88b transmembrane protein 88B [ Mus musculus (house mouse) ]

Gene ID: 320587, updated on 5-Mar-2024

Summary

Official Symbol
Tmem88bprovided by MGI
Official Full Name
transmembrane protein 88Bprovided by MGI
Primary source
MGI:MGI:2444329
See related
Ensembl:ENSMUSG00000073680 AllianceGenome:MGI:2444329
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
A230069A22Rik
Summary
Predicted to enable PDZ domain binding activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Orthologous to human TMEM88B (transmembrane protein 88B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in cerebellum adult (RPKM 15.3), cortex adult (RPKM 8.8) and 8 other tissues See more
Orthologs
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Genomic context

Location:
4 E2; 4 87.36 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (155866048..155870331, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (155781591..155785874, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E4739 Neighboring gene ATPase family, AAA domain containing 3A, opposite strand Neighboring gene von Willebrand factor A domain containing 1 Neighboring gene predicted gene, 54273 Neighboring gene STARR-seq mESC enhancer starr_12274 Neighboring gene ankyrin repeat domain 65 Neighboring gene mitochondrial ribosomal protein L20

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables PDZ domain binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in negative regulation of canonical Wnt signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033394.3NP_001028566.2  transmembrane protein 88B

    See identical proteins and their annotated locations for NP_001028566.2

    Status: VALIDATED

    Source sequence(s)
    AK031860, AK035998, AK038855
    Consensus CDS
    CCDS19040.1
    UniProtKB/Swiss-Prot
    A2AD92, Q3TYP4
    Related
    ENSMUSP00000095349.3, ENSMUST00000097742.3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    155866048..155870331 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)