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Cenpt centromere protein T [ Mus musculus (house mouse) ]

Gene ID: 320394, updated on 10-Oct-2019

Summary

Official Symbol
Cenptprovided by MGI
Official Full Name
centromere protein Tprovided by MGI
Primary source
MGI:MGI:2443939
See related
Ensembl:ENSMUSG00000036672
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
G630055P03Rik
Expression
Ubiquitous expression in CNS E14 (RPKM 19.8), limb E14.5 (RPKM 19.1) and 27 other tissues See more
Orthologs

Genomic context

See Cenpt in Genome Data Viewer
Location:
8; 8 D3
Exon count:
15
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (105844669..105855086, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (108368578..108375908, complement)

Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene glucose-fructose oxidoreductase domain containing 2 Neighboring gene RAN binding protein 10 Neighboring gene translin-associated factor X (Tsnax) interacting protein 1 Neighboring gene THAP domain containing 11 Neighboring gene nuclear transport factor 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cell division IEA
Inferred from Electronic Annotation
more info
 
chromosome organization ISO
Inferred from Sequence Orthology
more info
 
chromosome segregation ISO
Inferred from Sequence Orthology
more info
 
kinetochore assembly ISO
Inferred from Sequence Orthology
more info
 
mitotic cell cycle ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
chromosome IEA
Inferred from Electronic Annotation
more info
 
chromosome, centromeric region ISO
Inferred from Sequence Orthology
more info
 
kinetochore ISO
Inferred from Sequence Orthology
more info
 
nuclear body ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
centromere protein T
Names
CENP-T

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177150.2NP_796124.1  centromere protein T

    See identical proteins and their annotated locations for NP_796124.1

    Status: PROVISIONAL

    Source sequence(s)
    AK090340
    Consensus CDS
    CCDS22615.1
    UniProtKB/Swiss-Prot
    Q3TJM4
    Related
    ENSMUSP00000038188.4, ENSMUST00000040776.5
    Conserved Domains (2) summary
    pfam16171
    Location:1373
    CENP-T_N; Centromere kinetochore component CENP-T N-terminus
    cl23735
    Location:404507
    H4; Histone H4, one of the four histones, along with H2A, H2B and H3, which forms the eukaryotic nucleosome core; along with H3, it plays a central role in nucleosome formation; histones bind to DNA and wrap the genetic material into "beads on a string" in ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000074.6 Reference GRCm38.p6 C57BL/6J

    Range
    105844669..105855086 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011248407.2XP_011246709.1  centromere protein T isoform X2

    See identical proteins and their annotated locations for XP_011246709.1

    UniProtKB/Swiss-Prot
    Q3TJM4
    Conserved Domains (2) summary
    pfam16171
    Location:1373
    CENP-T_N; Centromere kinetochore component CENP-T N-terminus
    cl23735
    Location:404507
    H4; Histone H4, one of the four histones, along with H2A, H2B and H3, which forms the eukaryotic nucleosome core; along with H3, it plays a central role in nucleosome formation; histones bind to DNA and wrap the genetic material into "beads on a string" in ...
  2. XM_006531104.3XP_006531167.1  centromere protein T isoform X1

    Conserved Domains (2) summary
    pfam16171
    Location:1373
    CENP-T_N; Centromere kinetochore component CENP-T N-terminus
    cl23735
    Location:423526
    H4; Histone H4, one of the four histones, along with H2A, H2B and H3, which forms the eukaryotic nucleosome core; along with H3, it plays a central role in nucleosome formation; histones bind to DNA and wrap the genetic material into "beads on a string" in ...
  3. XM_006531107.4XP_006531170.1  centromere protein T isoform X4

    See identical proteins and their annotated locations for XP_006531170.1

    Conserved Domains (2) summary
    pfam16171
    Location:1269
    CENP-T_N; Centromere kinetochore component CENP-T N-terminus
    cl23735
    Location:319422
    H4; Histone H4, one of the four histones, along with H2A, H2B and H3, which forms the eukaryotic nucleosome core; along with H3, it plays a central role in nucleosome formation; histones bind to DNA and wrap the genetic material into "beads on a string" in ...
  4. XM_030243618.1XP_030099478.1  centromere protein T isoform X5

  5. XM_017312860.2XP_017168349.1  centromere protein T isoform X3

  6. XM_006531108.2XP_006531171.1  centromere protein T isoform X4

    See identical proteins and their annotated locations for XP_006531171.1

    Conserved Domains (2) summary
    pfam16171
    Location:1269
    CENP-T_N; Centromere kinetochore component CENP-T N-terminus
    cl23735
    Location:319422
    H4; Histone H4, one of the four histones, along with H2A, H2B and H3, which forms the eukaryotic nucleosome core; along with H3, it plays a central role in nucleosome formation; histones bind to DNA and wrap the genetic material into "beads on a string" in ...
  7. XM_030243617.1XP_030099477.1  centromere protein T isoform X5

  8. XM_030243619.1XP_030099479.1  centromere protein T isoform X6

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