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Atg8a Autophagy-related 8a [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32001, updated on 26-Aug-2021

Summary

Official Symbol
Atg8aprovided by FlyBase
Official Full Name
Autophagy-related 8aprovided by FlyBase
Primary source
FLYBASE:FBgn0052672
Locus tag
Dmel_CG32672
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Atg-8a; atg8; Atg8; ATG8; Atg8/LC3; ATG8/LC3; atg8a; atg8A; Atg8A; ATG8a; Atg8alpha; BcDNA:LD05816; CG1534; CG32672; dAtg8a; DmAtg8a; Dmel\CG32672; DrAtg8a; LC3; LC3/Atg8
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Genomic context

See Atg8a in Genome Data Viewer
Location:
9E6-9E7; 1-32 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.32 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (10764878..10768338, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (10658911..10662371, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene raspberry Neighboring gene Rabphilin Neighboring gene Transport and Golgi organization 5 Neighboring gene BTB (POZ) domain containing 9 Neighboring gene uncharacterized protein Neighboring gene Adenine nucleotide translocase 2

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the Atg8a gene: The Atg8a gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, and frog.
  • Orthologs

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables GABA receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein kinase binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein tag ISS
Inferred from Sequence or Structural Similarity
more info
 
enables ubiquitin protein ligase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in autophagosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in autophagy IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in autophagy of mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cellular response to nitrogen starvation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in determination of adult lifespan IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in determination of adult lifespan IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in larval midgut cell programmed cell death IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in macroautophagy IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in macroautophagy IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in regulation of autophagy IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of protein ubiquitination IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in amphisome IDA
Inferred from Direct Assay
more info
PubMed 
located_in autolysosome IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in autophagosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in autophagosome IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in autophagosome membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in type I terminal bouton IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
Autophagy-related 8a
Names
Atg8a-PA
Atg8a-PB
Atg8a-PC
Autophagy-specific gene 8a
CG32672-PA
CG32672-PB
CG32672-PC
autophagy-related 8 protein
autophagy-related 8a

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    10764878..10768338 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_167245.3NP_727447.1  Autophagy-related 8a, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_727447.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W2S2
    Related
    FBpp0071427, FBtr0071498
    Conserved Domains (1) summary
    cd01611
    Location:5116
    GABARAP; Ubiquitin domain of GABA-receptor-associated protein
  2. NM_001298158.1NP_001285087.1  Autophagy-related 8a, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285087.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    X2JJA8
    Related
    FBpp0312069, FBtr0346375
    Conserved Domains (1) summary
    cd01611
    Location:691
    GABARAP; Ubiquitin domain of GABA-receptor-associated protein
  3. NM_001298159.1NP_001285088.1  Autophagy-related 8a, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285088.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    X2JEE0
    Related
    FBpp0312070, FBtr0346376
    Conserved Domains (1) summary
    cd01611
    Location:7102
    GABARAP; Ubiquitin domain of GABA-receptor-associated protein
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