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RabX2 RabX2 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31971, updated on 5-Jul-2025
Official Symbol
RabX2provided by FlyBase
Official Full Name
RabX2provided by FlyBase
Primary source
FLYBASE:FBgn0030200
Locus tag
Dmel_CG2885
See related
AllianceGenome:FB:FBgn0030200
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG2885; Dmel\CG2885; DmRabX2
Summary
Predicted to enable GTPase activity. Predicted to be involved in Rab protein signal transduction; endocytic recycling; and exocytosis. Predicted to be located in vesicle. Predicted to be active in cytoplasmic vesicle and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
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Location:
9C1-9C1; 1-31 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (10417429..10418219)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (10311462..10312252)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Partner of Sld Five 3 Neighboring gene flapwing Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Odorant receptor 9a

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Rapidly evolving Rab GTPase paralogs and reproductive isolation in Drosophila. Hutter P. Adv Genet, 2007. PMID 17452244
  2. Regulation of lipid homeostasis by the TBC protein dTBC1D22 via modulation of the small GTPase Rab40 to facilitate lipophagy. Duan X, et al. Cell Rep, 2021 Aug 31. PMID 34469730
  3. X-linked small GTPase and OXPHOS genes are candidates for the genetic basis of hybrid inviability in Drosophila. Hutter P. Dev Genes Evol, 2002 Nov. PMID 12424521
  4. Excess of amino acid substitutions relative to polymorphism between X-linked duplications in Drosophila melanogaster. Thornton K, et al. Mol Biol Evol, 2005 Feb. PMID 15483321
  5. Negative regulation of Drosophila JAK-STAT signalling by endocytic trafficking. Vidal OM, et al. J Cell Sci, 2010 Oct 15. PMID 20841381, Free PMC Article

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in Rab protein signal transduction ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in endocytic recycling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in vesicle-mediated transport ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in synaptic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in trans-Golgi network transport vesicle IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in vesicle ISS
Inferred from Sequence or Structural Similarity
more info
  
Preferred Names
RabX2
Names
CG2885-PA
RabX2-PA

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    10417429..10418219
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132399.3 → NP_572627.1  RabX2

    See identical proteins and their annotated locations for NP_572627.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5IFC1, Q5IFC3, Q5IFC5, Q9W2V3
    Related
    FBpp0071383
    Conserved Domains (2) summary
    smart00175
    Location:8 → 171
    RAB; Rab subfamily of small GTPases
    cd00154
    Location:8 → 165
    Rab; Ras-related in brain (Rab) family of small guanosine triphosphatases (GTPases)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W2V3 Q9W2V3

Gene LinkOut

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